SCHEMBL6323489

SCHEMBL6323489

Cc1cccc(N2C(=O)c3cccc4cccc(c34)C2=O)c1C

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.79
KMT2A Q03164 4/20 0.79
BRD1 O95696 2/20 0.57
TAF1 P21675 2/20 0.57
BRPF1 P55201 2/20 0.57
BRD4 O60885 1/20 0.57
ALDH1A1 P00352 6/20 0.57
HPGD P15428 5/20 0.50
KDM4E B2RXH2 4/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
HSD17B10 Q99714 2/20 0.49
CASP1 P29466 1/20 0.49
MPI P34949 1/20 0.49
CACNA1B Q00975 1/20 0.49
APBA1 Q02410 1/20 0.49
LMNA P02545 1/20 0.49
POLB P06746 1/20 0.49
CYP1B1 Q16678 1/20 0.49
ERCC1 P07992 1/20 0.49
FEN1 P39748 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2924935 0.88 KMT2A (0.60) MEN1KMT2ABRD1TAF1BRPF1
SCHEMBL29168855 0.86 KMT2A (0.62) MEN1KMT2AALDH1A1LMNAPOLB
SCHEMBL30758617 0.86 KMT2A (0.62) MEN1KMT2AALDH1A1LMNAPOLB
SCHEMBL6323485 0.76 POLB (0.53) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL4966777 0.76 POLB (0.83) MEN1KMT2ABRD1TAF1BRPF1
SCHEMBL11610945 0.75 KDM5A (0.59) MEN1KMT2AALDH1A1HPGDPOLB
SCHEMBL9734396 0.75 CES1 (0.56) MEN1KMT2AALDH1A1LMNAPOLB
SCHEMBL14582057 0.74 MEN1 (0.64) MEN1KMT2ABRD1TAF1BRPF1
SCHEMBL24453236 0.74 ERCC1 (0.63) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL20735192 0.74 POLB (0.68) MEN1KMT2ABRD1TAF1BRPF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6921589-B2 Electroluminescent elements TORAY INDUSTRIES, INC. (JP) 2005-07-26 US disclosed
US-20020160227-A1 Electroluminescent elements KOHAMA AKIRA (JP) 2002-10-31 US disclosed
EP-1000998-B1 Electroluminescent element and devices TORAY INDUSTRIES (JP) 2002-10-09 EP disclosed
EP-1000998-A1 Electroluminescent element and devices TORAY INDUSTRIES, INC. (JP) 2000-05-17 EP disclosed