Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD1 | O95696 | 1/20 | 0.43 |
| ▸ | TAF1 | P21675 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323489 | 0.88 | MEN1 (0.79) | KMT2AMEN1ALDH1A1CASP1HSD17B10 | |
| SCHEMBL29168855 | 0.87 | KMT2A (0.62) | KMT2AMEN1ALDH1A1KDM5ANR1H2 | |
| SCHEMBL30758617 | 0.87 | KMT2A (0.62) | KMT2AMEN1ALDH1A1KDM5ANR1H2 | |
| SCHEMBL13084694 | 0.85 | KMT2A (0.74) | KMT2AMEN1ALDH1A1NR1H2NR1H3 | |
| SCHEMBL11610945 | 0.79 | KDM5A (0.59) | KMT2AMEN1ALDH1A1KDM5ANR1H2 | |
| SCHEMBL16656166 | 0.79 | KMT2A (0.66) | KMT2AMEN1ALDH1A1NR1H2NR1H3 | |
| SCHEMBL12021927 | 0.79 | DPP4 (0.64) | KMT2AMEN1ALDH1A1USP2MAPT | |
| SCHEMBL4728803 | 0.77 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL6323485 | 0.77 | POLB (0.53) | KMT2AMEN1ALDH1A1KDM5ANR1H2 | |
| SCHEMBL9734396 | 0.75 | CES1 (0.56) | KMT2AMEN1ALDH1A1KDM5ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404705-B2 | Naphthalene amidine imides | BASF SE (DE) | 2013-03-26 | — | — | US | disclosed |
| EP-1907484-B1 | NAPHTHALENE AMIDINE IMIDES | BASF SE (DE) | 2010-09-29 | — | — | EP | disclosed |
| US-20100202984-A1 | Naphthalene amidine imides | BASF SE (DE) | 2010-08-12 | — | — | US | disclosed |
| US-5886183-A | Naphthalenelactamimide fluorescence dyes | CIBA SPECIALTY CHEMICALS CORPORATOIN | 1999-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100202984-A1 | Naphthalene amidine imides | NES, TXN2, NAT1 | KMT2A 4175/4885MEN1 130/4885ALDH1A1 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.