SCHEMBL6323485

SCHEMBL6323485

Cc1cccc(N2C(=O)c3ccc4ccccc4c3C2=O)c1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.53
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
LMNA P02545 1/20 0.47
CASP3 P42574 1/20 0.46
ALDH1A1 P00352 3/20 0.43
FNTA P49354 1/20 0.42
FNTB P49356 1/20 0.42
MAPT P10636 2/20 0.42
HSD17B10 Q99714 2/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
TYMS P04818 1/20 0.41
DPP4 P27487 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
TSHR P16473 1/20 0.41
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28346733 0.85 POLB (0.72) POLBMEN1KMT2ALMNAALDH1A1
SCHEMBL30758617 0.78 KMT2A (0.62) POLBMEN1KMT2ALMNACASP3
SCHEMBL29168855 0.78 KMT2A (0.62) POLBMEN1KMT2ALMNACASP3
SCHEMBL2924935 0.77 KMT2A (0.60) MEN1KMT2ALMNACASP3ALDH1A1
SCHEMBL6323489 0.76 MEN1 (0.79) POLBMEN1KMT2ALMNAALDH1A1
SCHEMBL299840 0.74 HSPA1A (0.56) POLBMEN1KMT2ALMNAALDH1A1
SCHEMBL300361 0.72 DPP4 (0.60) POLBMEN1KMT2AALDH1A1MAPT
SCHEMBL10396140 0.71 PTPN1 (0.51) POLBMEN1KMT2ALMNAALDH1A1
SCHEMBL22203805 0.71 POLB (0.79) POLBMEN1KMT2AALDH1A1FNTA
SCHEMBL4109839 0.71 DNMT1 (0.50) POLBMEN1KMT2ALMNACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6921589-B2 Electroluminescent elements TORAY INDUSTRIES, INC. (JP) 2005-07-26 US disclosed
US-20020160227-A1 Electroluminescent elements KOHAMA AKIRA (JP) 2002-10-31 US disclosed
EP-1000998-B1 Electroluminescent element and devices TORAY INDUSTRIES (JP) 2002-10-09 EP disclosed
EP-1000998-A1 Electroluminescent element and devices TORAY INDUSTRIES, INC. (JP) 2000-05-17 EP disclosed