⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21904726 | 1.00 | ALDH1A1 (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL6494188 | 1.00 | ALDH1A1 (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL21816618 | 0.92 | — | — | |
| Trifluoroacetic Acid SCHEMBL30657022 | 0.91 | — | — | |
| Trifluoroacetic Acid SCHEMBL7814389 | 0.91 | ALDH1A1 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL2484766 | 0.91 | ALDH1A1 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL474 | 0.91 | — | — | |
| Trifluoroacetic Acid SCHEMBL4598430 | 0.91 | — | — | |
| Trifluoroacetic Acid SCHEMBL28579679 | 0.88 | ALDH1A1 (0.38) | — | |
| Trifluoroacetic Acid SCHEMBL4700635 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110049985-B | Heterocyclic sulfones as ROR gamma modulators | 百时美施贵宝公司 | 2022-05-31 | — | — | CN | claimed |
| CN-119330972-A | PARP7 inhibitor and application thereof | 重庆华森英诺生物科技有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-115715289-B | Polyarylate and application thereof | 江苏先声药业有限公司 | 2024-12-03 | — | — | CN | disclosed |
| US-20240360157-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2024-10-31 | — | — | US | disclosed |
| CN-115745971-B | PARP7 inhibitor and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-113767092-B | Di-heterocyclic carbonyl substituted dihydropyrazoles, their preparation and their use in medicine | 劲方医药科技(上海)有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118005640-A | GCN2 inhibitors and uses thereof | 默克专利股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-112368289-B | C26-linked rapamycin analogues as MTOR inhibitors | 锐新医药公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-111918651-B | GCN2 inhibitors and uses thereof | 默克专利股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-111978325-B | Imidazopyridazine MNK1/MNK2 kinase inhibitor, and preparation method and application thereof | 中国药科大学 | 2023-11-17 | — | — | CN | disclosed |
| US-20220041597-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | FORMA THERAPEUTICS, INC. | 2022-02-10 | — | — | US | disclosed |
| CN-109952300-B | 5-or 8-substituted imidazo [1,5-a ] pyridines | 百济神州有限公司 | 2022-01-18 | — | — | CN | disclosed |
| CN-113767092-A | Bis-heterocyclic carbonyl substituted dihydropyrazole compound, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2021-12-07 | — | — | CN | disclosed |
| EP-3891148-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |
| CN-107624110-B | Lysyl oxidase-like 2 inhibitors and uses thereof | 法玛克亚公司 | 2021-01-26 | — | — | CN | disclosed |
| WO-2020114494-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-06-11 | — | — | WO | disclosed |
| US-8569299-B2 | Prolylcarboxypeptidase inhibitors | MERCK SHARP & DOHME CORP (US) | 2013-10-29 | — | — | US | disclosed |
| US-20130143859-A1 | NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-06-06 | — | — | US | disclosed |
| US-6977263-B2 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-12-20 | — | — | US | disclosed |
| US-20050228018-A1 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-13 | — | — | US | disclosed |