Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761440 | 0.83 | CHRNA7 (0.60) | CHRNA7PARP1UCHL1HDAC1 | |
| SCHEMBL6329821 | 0.83 | CHRNA7 (0.53) | CHRNA7HTR3ACHRNB4CHRNA3KDM4E | |
| SCHEMBL15663026 | 0.80 | CHRNA7 (0.60) | CHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL6330678 | 0.80 | CHRNA7 (0.60) | CHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL13768179 | 0.77 | CHRNB4 (0.48) | CHRNB4CHRNA3PARP1HDAC1 | |
| SCHEMBL6329995 | 0.77 | GPR119 (0.47) | CHRNA7HTR3ACHRNB4CHRNA3KDM4E | |
| SCHEMBL929426 | 0.77 | CHRNA7 (0.64) | CHRNA7HTR3ACHRNB4CHRNA3KDM4E | |
| SCHEMBL6201547 | 0.72 | CHRNA7 (0.74) | CHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL13768039 | 0.72 | CHRNB2 (0.39) | CHRNA7CHRNB4CHRNA3PARP1HDAC1 | |
| SCHEMBL13768040 | 0.71 | HDAC1 (0.38) | CHRNB4CHRNA3PARP1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065178-A1 | Substituted diazabicycloakane derivatives | ABBOTT LABORATORIES | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065178-A1 | Substituted diazabicycloakane derivatives | CHRNA7, CHRNA1, CHRNA5 | CHRNA7 1/4885HTR3A 160/4885CHRNB4 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.