Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HBB | P68871 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643854 | 0.80 | L3MBTL1 (0.47) | APPESR1MAPTLMNAHBB | |
| SCHEMBL16416312 | 0.80 | APP (0.42) | APPESR1MAPTLMNAHBB | |
| SCHEMBL6880339 | 0.80 | ESR1 (0.42) | APPEGFRESR1MAPTLMNA | |
| SCHEMBL11050700 | 0.80 | ALDH1A1 (0.48) | EGFRERBB2MAPTLMNAHBB | |
| SCHEMBL8149499 | 0.78 | ALDH1A1 (0.50) | EGFRERBB2MAPTLMNAHBB | |
| Hydrochloric Acid SCHEMBL9661413 | 0.78 | L3MBTL1 (0.46) | APPESR1MAPTLMNAHBB | |
| SCHEMBL22542480 | 0.78 | TAAR1 (0.41) | APPESR1MAPTLMNAHBB | |
| SCHEMBL28733423 | 0.78 | APP (0.41) | APPESR1MAPTLMNAHBB | |
| SCHEMBL6738124 | 0.77 | EGFR (0.46) | EGFRERBB2MAPTLMNAMEN1 | |
| SCHEMBL905253 | 0.77 | EGFR (0.49) | EGFRERBB2MAPTLMNAHBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209320-A1 | Anti-cancer compounds and methods of use thereof | GTX, INC. | 2005-09-22 | — | — | US | disclosed |
| US-6303569-B1 | POLYMERIC-BASED DOUBLE PRODRUGS HAVING REVERSIBLE LINKAGES INVOLVING AMINO OR HYDROXYL MOIETIES OF CHEMICAL COMPOUNDS AND BIOLOGICALLY ACTIVE MATERIALS SUCH AS ENZYMES, PROTEINS | ENZON, INC. | 2001-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209320-A1 | Anti-cancer compounds and methods of use thereof | AR, BRDT, BAD | APP 4717/4885EGFR 18/4885ERBB2 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.