SCHEMBL6323926

SCHEMBL6323926

Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.76
CA12 O43570 4/20 0.72
CA1 P00915 4/20 0.72
CA2 P00918 4/20 0.72
CA9 Q16790 4/20 0.72
CA4 P22748 2/20 0.72
CA6 P23280 2/20 0.72
CA5A P35218 2/20 0.72
CA7 P43166 2/20 0.72
CA13 Q8N1Q1 2/20 0.72
CA14 Q9ULX7 2/20 0.72
TP53 P04637 1/20 0.72
PPARG P37231 1/20 0.68
RAB9A P51151 1/20 0.68
RXFP1 Q9HBX9 1/20 0.68
NR2E3 Q9Y5X4 1/20 0.68
NCOR2 Q9Y618 1/20 0.68
KMT2A Q03164 4/20 0.63
MEN1 O00255 3/20 0.63
ALDH1A1 P00352 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1928662 0.91 CA12 (0.85) LMNACA12CA1CA2CA9
SCHEMBL6243996 0.91 CA12 (0.85) LMNACA12CA1CA2CA9
SCHEMBL5184884 0.88 KMT2A (0.77) LMNACA12CA1CA2CA9
SCHEMBL5184973 0.87 LMNA (0.79) LMNACA12CA1CA2CA9
SCHEMBL6322949 0.87 CA1 (0.74) LMNACA12CA1CA2CA9
SCHEMBL8756695 0.87 CA12 (0.70) LMNACA12CA1CA2CA9
SCHEMBL1395600 0.86 CA12 (0.78) LMNACA12CA1CA2CA9
SCHEMBL23486695 0.86 LMNA (0.88) LMNACA12CA1CA2CA9
SCHEMBL27885 0.86 LMNA (1.00) LMNACA12CA1CA2CA9
SCHEMBL7276663 0.86 LMNA (0.63) LMNACA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4037909-B1 POLYMORPHIC FORMS OF N-(4-((4-(3-PHENYLUREIDO)PHENYL)SULFONYL)PHENYL)BENZOLSULFONAMIDE AND HEAT SENSITIVE RECORDING MEDIA CONTAINING THE SAME KOEHLER PAPER SE (DE) 2023-03-29 EP disclosed
WO-2021105499-A1 POLYMORPHIC FORMS OF N-(4-((4-(3-PHENYLUREIDO)PHENYL)SULFONYL)PHENYL)BENZOLSULFONAMIDE PAPIERFABRIK AUGUST KOEHLER SE (DE) 2021-06-03 WO disclosed
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
JP-2004189691-A CRYSTAL TRANSFORMATION OF n-BUTYL 4-(3-(p-TOLUENESULFONYL)UREIDO)BENZOATE AS COLOR DEVELOPING AGENT FOR THERMAL RECORDING MEDIUM OJI PAPER CO LTD 2004-07-08 JP disclosed
JP-2004189691-A CRYSTAL TRANSFORMATION OF n-BUTYL 4-(3-(p-TOLUENESULFONYL)UREIDO)BENZOATE AS COLOR DEVELOPING AGENT FOR THERMAL RECORDING MEDIUM OJI PAPER CO LTD 2004-07-08 JP disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed