Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.74 |
| ▸ | CA2 | P00918 | 4/20 | 0.74 |
| ▸ | CA9 | Q16790 | 4/20 | 0.74 |
| ▸ | CA12 | O43570 | 3/20 | 0.74 |
| ▸ | CA4 | P22748 | 2/20 | 0.74 |
| ▸ | CA6 | P23280 | 2/20 | 0.74 |
| ▸ | CA5A | P35218 | 2/20 | 0.74 |
| ▸ | CA7 | P43166 | 2/20 | 0.74 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.74 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | PPARG | P37231 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.67 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243996 | 0.89 | CA12 (0.85) | CA1CA2CA9CA12CA4 | |
| SCHEMBL1928662 | 0.89 | CA12 (0.85) | CA1CA2CA9CA12CA4 | |
| SCHEMBL6323926 | 0.87 | LMNA (0.76) | CA1CA2CA9CA12CA4 | |
| SCHEMBL5184884 | 0.87 | KMT2A (0.77) | CA1CA2CA9CA12CA4 | |
| SCHEMBL6323791 | 0.86 | ALDH1A1 (0.56) | CA1CA2CA9CA12CA4 | |
| SCHEMBL8756695 | 0.86 | CA12 (0.70) | CA1CA2CA9CA12CA4 | |
| SCHEMBL29973557 | 0.85 | CA1 (1.00) | CA1CA2CA9CA12CA4 | |
| SCHEMBL1395600 | 0.85 | CA12 (0.78) | CA1CA2CA9CA12CA4 | |
| SCHEMBL6326204 | 0.84 | LMNA (0.67) | CA1CA2CA9CA12CA4 | |
| SCHEMBL6329251 | 0.84 | NLRP3 (0.57) | CA1CA2CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065178-A1 | Substituted diazabicycloakane derivatives | ABBOTT LABORATORIES | 2005-03-24 | — | — | US | disclosed |
| US-6858565-B2 | Thermosensitive recording material and novel color developer compounds | OJI PAPER CO., LTD. (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20030040434-A1 | Thermosensitive recording material and novel color developer compounds | OJI PAPER CO., LTD. (JP) | 2003-02-27 | — | — | US | disclosed |
| EP-1264707-A2 | Thermosensitive recording material and novel color developer compounds | OJI PAPER CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065178-A1 | Substituted diazabicycloakane derivatives | CHRNA7, CHRNA1, CHRNA5 | CA1 2328/4885CA2 2740/4885CA9 3310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.