SCHEMBL6324043

SCHEMBL6324043

Cc1ccc(S(=O)(=O)NC(=O)Nc2cccc(C(=O)OCc3ccccc3)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.61
LMNA P02545 2/20 0.61
TCF4 P15884 1/20 0.53
CTNNB1 P35222 1/20 0.53
MAPT P10636 3/20 0.53
ALDH1A1 P00352 1/20 0.52
MAPK1 P28482 1/20 0.52
TP53 P04637 1/20 0.51
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
KMT2A Q03164 2/20 0.50
PPIA P62937 1/20 0.50
MEN1 O00255 1/20 0.50
KCNA1 Q09470 1/20 0.49
KCNAB1 Q14722 1/20 0.49
HTT P42858 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
GAA P10253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6324694 0.91 RAB9A (0.60) RAB9ALMNAMAPTALDH1A1MAPK1
SCHEMBL6326605 0.90 MAPT (0.63) RAB9ALMNATCF4CTNNB1MAPT
SCHEMBL6725222 0.88 LMNA (0.65) RAB9ALMNAMAPTALDH1A1TP53
SCHEMBL1928909 0.88 LMNA (0.61) RAB9ALMNATCF4CTNNB1MAPT
SCHEMBL6330701 0.88 TP53 (0.64) RAB9ALMNATCF4CTNNB1MAPT
SCHEMBL1929671 0.86 LMNA (0.58) RAB9ALMNATCF4CTNNB1ALDH1A1
SCHEMBL1929599 0.86 LMNA (0.58) RAB9ALMNATCF4CTNNB1MAPT
SCHEMBL6324534 0.85 LMNA (0.57) RAB9ALMNATCF4CTNNB1MAPT
SCHEMBL1929143 0.85 LMNA (0.57) RAB9ALMNATCF4CTNNB1MAPT
SCHEMBL1930029 0.85 LMNA (0.57) RAB9ALMNATCF4CTNNB1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050065178-A1 Substituted diazabicycloakane derivatives ABBOTT LABORATORIES 2005-03-24 US disclosed
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065178-A1 Substituted diazabicycloakane derivatives CHRNA7, CHRNA1, CHRNA5 RAB9A 1315/4885LMNA 1975/4885TCF4 3102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.