Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716115 | 0.84 | SLC6A2 (0.42) | TRPM8KDM4EATMALOX5SLC6A3 | |
| SCHEMBL1231239 | 0.84 | SLC6A2 (0.42) | TRPM8KDM4EATMALOX5SLC6A3 | |
| SCHEMBL14909537 | 0.84 | SLC6A2 (0.42) | TRPM8KDM4EATMALOX5SLC6A3 | |
| SCHEMBL531655 | 0.82 | RIPK1 (0.42) | CYP2C19TRPM8ALDH1A1KDM4EATM | |
| SCHEMBL19305428 | 0.82 | RIPK1 (0.42) | CYP2C19TRPM8ALDH1A1KDM4EATM | |
| SCHEMBL19305426 | 0.82 | RIPK1 (0.42) | CYP2C19TRPM8ALDH1A1KDM4EATM | |
| SCHEMBL16632995 | 0.81 | EPHX1 (0.41) | ALDH1A1LMNAEPHX1 | |
| SCHEMBL4345757 | 0.81 | TRPA1 (0.41) | TRPM8ALDH1A1KDM4EATMALOX5 | |
| SCHEMBL1274248 | 0.78 | KDM4E (0.39) | CYP2C19TRPM8ALDH1A1KDM4EATM | |
| SCHEMBL4352633 | 0.78 | KDM4E (0.39) | CYP2C19TRPM8ALDH1A1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6914160-B1 | Oxytocin inhibitors | PFIZER INC (US) | 2005-07-05 | — | — | US | disclosed |