SCHEMBL632439

SCHEMBL632439

CCNc1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.48
MAPT P10636 3/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
RAB9A P51151 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
RECQL P46063 2/20 0.47
LMNA P02545 3/20 0.47
ADRA2A P08913 3/20 0.47
ADRA2B P18089 2/20 0.47
ADRA2C P18825 2/20 0.47
P2RX3 P56373 1/20 0.44
ALDH1A1 P00352 4/20 0.43
NPC1 O15118 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
CYP2A6 P11509 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1924678 0.97 CNR2 (0.47) CNR2MAPTMEN1KMT2ARAB9A
Trimethylammonium SCHEMBL7802299 0.93 CNR2 (0.49) CNR2MAPTMEN1KMT2ARAB9A
SCHEMBL12355492 0.87 P2RX3 (0.48) P2RX3ALDH1A1
SCHEMBL526383 0.86 MAPT (0.58) MAPTMEN1KMT2ARECQLLMNA
Hydrochloric Acid SCHEMBL9181167 0.83 MAPT (0.56) MAPTMEN1KMT2ARECQLLMNA
Ammonia Solution, Strong SCHEMBL28486254 0.83 MAPT (0.56) MAPTMEN1KMT2ARECQLLMNA
Ammonia Solution, Strong SCHEMBL28483632 0.83 MAPT (0.56) MAPTMEN1KMT2ARECQLLMNA
SCHEMBL15478385 0.81 CNR2 (0.43) CNR2MAPTMEN1KMT2ARAB9A
SCHEMBL1801536 0.80 NR1I2 (0.56) CNR2MAPTMEN1KMT2ARAB9A
SCHEMBL22874671 0.80 MAOB (0.57) MAPTMEN1KMT2ARAB9AP2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250387385-A1 TREATMENT FOR GLOMERULAR DISEASES ZYDUS LIFESCIENCES LIMITED (IN) 2025-12-25 US claimed
EP-4565233-A1 TREATMENT FOR APLASTIC ANEMIA (AA) Zydus Lifesciences Limited (IN) 2025-06-11 EP claimed
EP-4539934-A1 TREATMENT FOR GLOMERULAR DISEASES Zydus Lifesciences Limited (IN) 2025-04-23 EP claimed
CN-119816306-A Treatment of Aplastic Anemia (AA) 载度思生命科学有限公司 2025-04-11 CN claimed
CN-119486735-A For the treatment of glomerular diseases 载度思生命科学有限公司 2025-02-18 CN claimed
CN-119212524-A Perovskite solar cell with chiral amine post-treatment function and preparation method thereof 桂林电子科技大学 2024-12-27 CN claimed
CN-119053210-A Mesoscopic perovskite solar cell based on chiral perovskite heterojunction and preparation method thereof 桂林电子科技大学 2024-11-29 CN claimed
CN-118726998-A Preparation method for preparing benzyl carboxylic acid compound from benzylamine and carbon dioxide 哈尔滨工业大学(深圳) 2024-10-01 CN claimed
CN-117801815-B Chiral quasi two-dimensional perovskite film capable of emitting circularly polarized light and preparation method thereof 天津大学 2024-08-09 CN claimed
US-20240173314-A1 TREATMENT OF SICKLE CELL ANAEMIA ZYDUS LIFESCIENCES LTD. (IN) 2024-05-30 US claimed
EP-0910660-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES BAYER AG (DE) 1999-04-28 EP claimed
EP-0906267-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE 1-PHENYLETHYLAMINES BAYER AG (DE) 1999-04-07 EP claimed
WO-1998003465-A1 PROCESS FOR PREPARING RACEMIC PHENETHYLAMINES BAYER AKTIENGESELLSCHAFT (DE) 1998-01-29 WO claimed
WO-1997049665-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE 1-PHENYLETHYLAMINES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-31 WO claimed
WO-1997046698-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-11 WO claimed
US-5144077-A PROCESS FOR WORKING UP THE CRYSTALLIZATION MOTHER LIQUOR FROM THE RESOLUTION OF THE RACEMATE OF 1-(4-CHLOROPHENYL)-ETHYLAMINE BAYER AKTIENGESELLSCHAFT (DE) 1992-09-01 US claimed
EP-0208404-B1 BENZOTHIAZINE DIOXIDE DERIVATIVES PFIZER INC. (US) 1990-08-29 EP claimed
EP-0208404-A2 Benzothiazine dioxide derivatives PFIZER INC. (US) 1987-01-14 EP claimed
US-4634448-A CATIONIC TRIAZINE DYES NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-01-06 US claimed
US-4623486-A [4-substituted benzoyloxy]-N-substituted-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides having anti-arthritic activity PFIZER INC. (US) 1986-11-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250387385-A1 TREATMENT FOR GLOMERULAR DISEASES SSB, GRN, ALB CNR2 3667/4885MAPT 292/4885MEN1 1156/4885
US-20240173314-A1 TREATMENT OF SICKLE CELL ANAEMIA HBG1, HBB, HBG2 CNR2 2094/4885MAPT 4146/4885MEN1 3116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.