Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328404 | 0.88 | ADK (0.32) | HPRT1ADK | |
| SCHEMBL6902586 | 0.85 | HPRT1 (0.43) | HPRT1ADK | |
| SCHEMBL6324412 | 0.80 | HPRT1 (0.39) | HPRT1 | |
| SCHEMBL6322296 | 0.79 | HPRT1 (0.39) | HPRT1 | |
| SCHEMBL6321207 | 0.79 | HPRT1 (0.37) | HPRT1 | |
| SCHEMBL6329654 | 0.77 | HPRT1 (0.37) | HPRT1 | |
| SCHEMBL6322355 | 0.77 | HPRT1 (0.37) | HPRT1 | |
| SCHEMBL6902812 | 0.73 | FGFR1 (0.39) | HPRT1ADK | |
| SCHEMBL6329303 | 0.71 | ADORA2A (0.46) | HPRT1 | |
| SCHEMBL6905054 | 0.71 | HPRT1 (0.45) | HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080053-A1 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | BIOCRYST PHARMACEUTICALS, INC. (US) | 2005-04-14 | — | — | US | claimed |
| US-20050080053-A1 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | BIOCRYST PHARMACEUTICALS, INC. (US) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080053-A1 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | POLR2H, NSUN2, RNASEH1 | HPRT1 680/4885ADK 1903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.