SCHEMBL6324438

SCHEMBL6324438

COC(=O)c1cccc(NC(=O)NS(=O)(=O)c2ccccc2C)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.60
RAB9A P51151 8/20 0.54
CA12 O43570 2/20 0.54
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA9 Q16790 2/20 0.54
NPC1 O15118 6/20 0.53
MAPT P10636 5/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
GPR17 Q13304 1/20 0.53
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
POLB P06746 2/20 0.51
TCF4 P15884 1/20 0.51
CTNNB1 P35222 1/20 0.51
ALDH1A1 P00352 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6331689 0.90 RAB9A (0.61) RAB9ACA12CA1CA2CA9
SCHEMBL1928894 0.90 RAB9A (0.52) IDH1RAB9ACA12CA1CA2
SCHEMBL1931137 0.88 SMN1; SMN2 (0.50) IDH1RAB9ACA12CA1CA2
SCHEMBL1931062 0.88 SMN1; SMN2 (0.50) IDH1RAB9ACA12CA1CA2
SCHEMBL1929853 0.87 SMN1; SMN2 (0.49) IDH1RAB9ACA12CA1CA2
SCHEMBL1929112 0.87 SMN1; SMN2 (0.49) IDH1RAB9ACA12CA1CA2
SCHEMBL1929593 0.87 SMN1; SMN2 (0.49) IDH1RAB9ACA12CA1CA2
SCHEMBL1930264 0.87 SMN1; SMN2 (0.49) IDH1RAB9ACA12CA1CA2
SCHEMBL1928184 0.87 SMN1; SMN2 (0.49) IDH1RAB9ACA12CA1CA2
SCHEMBL6331093 0.87 ALDH1A1 (0.58) IDH1RAB9ACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed