Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 10/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630963 | 1.00 | FBP1 (1.00) | FBP1CYP1A2CYP2C9ALDH1A1TDP1 | |
| SCHEMBL630964 | 1.00 | FBP1 (1.00) | FBP1CYP1A2CYP2C9ALDH1A1TDP1 | |
| SCHEMBL30295762 | 1.00 | FBP1 (1.00) | FBP1CYP1A2CYP2C9ALDH1A1TDP1 | |
| SCHEMBL1237402 | 0.82 | FBP1 (0.69) | FBP1ALDH1A1KDM4EPOLB | |
| SCHEMBL1237403 | 0.82 | FBP1 (0.69) | FBP1ALDH1A1KDM4EPOLB | |
| SCHEMBL8628810 | 0.81 | FBP1 (0.69) | FBP1CYP1A2CYP2C9ALDH1A1TDP1 | |
| SCHEMBL8628812 | 0.81 | FBP1 (0.69) | FBP1CYP1A2CYP2C9ALDH1A1TDP1 | |
| SCHEMBL1237309 | 0.81 | FBP1 (0.69) | FBP1CYP1A2ALDH1A1TDP1NPC1 | |
| SCHEMBL1237311 | 0.81 | FBP1 (0.69) | FBP1CYP1A2ALDH1A1TDP1NPC1 | |
| SCHEMBL28479114 | 0.81 | FBP1 (0.69) | FBP1CYP1A2NPC1RAB9ACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315482-B2 | Derivatives useful as antiviral agents | INSTITUT PASTEUR (FR) | 2016-04-19 | — | — | US | disclosed |
| US-20130210886-A1 | Novel Derivatives Useful as Antiviral Agents | INSTITUT PASTEUR (FR) | 2013-08-15 | — | — | US | disclosed |
| EP-2598495-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | Institut Pasteur (FR) | 2013-06-05 | — | — | EP | disclosed |
| EP-2420495-A1 | Novel derivatives useful as antiviral agents | Institut Pasteur (FR) | 2012-02-22 | — | — | EP | disclosed |
| WO-2012014181-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | INSTITUT PASTEUR (FR) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130210886-A1 | Novel Derivatives Useful as Antiviral Agents | MAVS, IRF3, IFNAR1 | FBP1 1867/4885CYP1A2 1951/4885CYP2C9 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.