Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TACR2 | P21452 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23085881 | 0.95 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAPTPN1SMN1; SMN2 | |
| SCHEMBL29446267 | 0.85 | TACR2 (0.62) | ALDH1A1KDM4ELMNASMN1; SMN2TACR2 | |
| SCHEMBL584489 | 0.85 | TACR2 (0.62) | ALDH1A1KDM4ELMNASMN1; SMN2TACR2 | |
| SCHEMBL161066 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KDM4ESMN1; SMN2APPHPGD | |
| Anisaldehyde SCHEMBL8699445 | 0.82 | PDCD1 (0.53) | ALDH1A1KDM4ESMN1; SMN2APPHTT | |
| SCHEMBL4363943 | 0.82 | MAOB (0.57) | ALDH1A1PTPN1SMN1; SMN2MAOBHPGD | |
| SCHEMBL22116364 | 0.82 | PTPN1 (0.60) | ALDH1A1PTPN1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL16294326 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4ESMN1; SMN2APPNPC1 | |
| SCHEMBL662145 | 0.82 | TACR2 (0.75) | ALDH1A1KDM4ELMNASMN1; SMN2TACR2 | |
| SCHEMBL1609108 | 0.82 | TACR2 (0.75) | ALDH1A1KDM4ELMNASMN1; SMN2TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050228017-A1 | Novel anticancer compounds | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE | 2005-10-13 | — | — | US | disclosed |
| US-6870035-B2 | Black dye mixtures of fiber-reactive azo dyes, methods for their preparation and use thereof for dyeing hydroxy-and/or carboxamido-containing fiber material | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2005-03-22 | — | — | US | disclosed |
| EP-1442018-A1 | NOVEL ANTICANCER COMPOUNDS | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003037865-A1 | NOVEL ANTICANCER COMPOUNDS | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228017-A1 | Novel anticancer compounds | TP53, ABCG2, MCL1 | ALDH1A1 211/4885KDM4E 2416/4885LMNA 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.