Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 17/20 | 0.58 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4150819 | 0.99 | HPGD (0.56) | HPGDGRIA3GRIA4ALDH1A1SMN1; SMN2 | |
| SCHEMBL6323082 | 0.96 | HPGD (0.52) | HPGDGRIA3GRIA4ALDH1A1SMN1; SMN2 | |
| SCHEMBL6331446 | 0.85 | PLA2G7 (0.43) | HPGDGRIA3GRIA4ALDH1A1SMN1; SMN2 | |
| SCHEMBL4150653 | 0.80 | SMYD3 (0.66) | HPGDGRIA3GRIA4ALDH1A1SMN1; SMN2 | |
| SCHEMBL6324361 | 0.79 | PDK2 (0.43) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4149825 | 0.77 | HPGD (0.51) | HPGDSMN1; SMN2POLB | |
| SCHEMBL4968804 | 0.76 | PDE4A (0.47) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL6332114 | 0.76 | PDE4A (0.47) | SMN1; SMN2POLB | |
| SCHEMBL31315369 | 0.76 | HPGD (0.56) | HPGDGRIA3GRIA4ALDH1A1 | |
| SCHEMBL6843232 | 0.75 | PDE4A (0.46) | HPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-05-19 | — | — | US | disclosed |
| WO-2004080970-A1 | NOVEL BICYCLIC AROMATIC COMPOUNDS, THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | F12, F2, F11 | HPGD 1428/4885GRIA3 4111/4885GRIA4 4449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.