Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL927342 | 1.00 | DPP4 (0.45) | DPP4DPP7CCR5DPP8KDM1A | |
| SCHEMBL654325 | 0.91 | DPP4 (0.42) | DPP4DPP7CCR5DPP8KDM1A | |
| SCHEMBL649724 | 0.91 | DPP4 (0.42) | DPP4DPP7CCR5DPP8KDM1A | |
| SCHEMBL3335897 | 0.91 | DPP4 (0.45) | DPP4DPP7CCR5DPP8KDM1A | |
| SCHEMBL1586795 | 0.81 | GPR119 (0.54) | — | |
| SCHEMBL1586797 | 0.81 | GPR119 (0.54) | — | |
| SCHEMBL929459 | 0.81 | GPR119 (0.54) | — | |
| SCHEMBL7687290 | 0.79 | CCR5 (0.42) | CCR5CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3575935 | 0.79 | CCR5 (0.42) | CCR5CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5130929 | 0.79 | CCR5 (0.42) | CCR5CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065178-A1 | Substituted diazabicycloakane derivatives | ABBOTT LABORATORIES | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065178-A1 | Substituted diazabicycloakane derivatives | CHRNA7, CHRNA1, CHRNA5 | DPP4 1461/4885DPP7 510/4885CCR5 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.