SCHEMBL6324942

SCHEMBL6324942

C=C(C)C(=O)Oc1c(OCC)cc(C2(c3cc(OCC)c(OC(=O)C(=C)C)c(C)c3OCC)c3ccccc3-c3ccccc32)c(OCC)c1C

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.38
TP53 P04637 2/20 0.38
TSHR P16473 3/20 0.35
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GAA P10253 4/20 0.34
POLB P06746 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
GLA P06280 1/20 0.33
PDK2 Q15119 3/20 0.33
LMNA P02545 1/20 0.33
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2866535 0.91 TSHR (0.36) MAPTTP53TSHRALDH1A1KDM4E
SCHEMBL6324549 0.89 PDK2 (0.35) TP53ALDH1A1KDM4EGAAPDK2
SCHEMBL6328897 0.88 TSHR (0.34) MAPTTP53TSHRALDH1A1KDM4E
SCHEMBL6323480 0.86 TSHR (0.33) MAPTTP53TSHRKDM4EL3MBTL1
SCHEMBL7072257 0.83 PDK2 (0.34) MAPTTSHRALDH1A1GAAPOLB
SCHEMBL6322648 0.82 ELANE (0.33) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL2873370 0.81 PDK2 (0.36) MAPTTP53TSHRALDH1A1HPGD
SCHEMBL31068446 0.81 PDK2 (0.36) MAPTTP53TSHRALDH1A1HPGD
SCHEMBL6323519 0.80 PDK2 (0.36) MAPTTP53ALDH1A1PDK2NPC1
SCHEMBL6330393 0.79 ELANE (0.35) MAPTALDH1A1KDM4EHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10611869-B2 Curable composition and cured product AGC Inc. (JP) 2020-04-07 US disclosed
US-20190218325-A1 CURABLE COMPOSITION AND CURED PRODUCT AGC Inc. (JP) 2019-07-18 US disclosed
US-20050185232-A1 Volume hologram recording photosensitive composition and its use NIPPON PAINT CO., LTD. (JP) 2005-08-25 US disclosed
US-20030096172-A1 Hologram recording material composition and hologram recording medium DAISO CO., LTD. (JP) 2003-05-22 US disclosed