SCHEMBL6324964

SCHEMBL6324964

C[Si](Cl)(Cl)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
KCNN4 O15554 5/20 0.39
MAPK1 P28482 2/20 0.39
ALDH1A1 P00352 3/20 0.38
CYP1A2 P05177 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
ALOX15 P16050 1/20 0.36
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
CYP3A4 P08684 2/20 0.34
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6322919 0.84 TSHR (0.43) TSHRKCNN4MAPK1ALDH1A1CYP1A2
SCHEMBL6602971 0.79 ALDH1A1 (0.41) TSHRKCNN4MAPK1ALDH1A1CYP1A2
SCHEMBL6321916 0.78 TSHR (0.48) TSHRKCNN4MAPK1ALDH1A1CYP1A2
SCHEMBL3743994 0.74 KCNN4 (0.39) TSHRKCNN4MAPK1ALDH1A1TAAR1
SCHEMBL6860477 0.74 ALDH1A1 (0.43) TSHRKCNN4MAPK1ALDH1A1CYP1A2
SCHEMBL6602963 0.74 ALDH1A1 (0.39) TSHRKCNN4MAPK1ALDH1A1CYP1A2
SCHEMBL10332646 0.74 KCNN4 (0.39) TSHRKCNN4MAPK1ALDH1A1TAAR1
SCHEMBL10332647 0.74 KCNN4 (0.43) TSHRKCNN4MAPK1ALDH1A1CYP1A2
SCHEMBL7053156 0.72 ALDH1A1 (0.44) TSHRKCNN4MAPK1ALDH1A1CYP1A2
SCHEMBL7754101 0.72 MAPK1 (0.42) TSHRKCNN4MAPK1ALDH1A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130153263-A1 INORGANIC NANOFILLER, PARTIAL DISCHARGE RESISTANT ENAMELED WIRE INCLUDING THE SAME, AND PREPARING METHOD OF THE ENAMELED WIRE SEJONG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2013-06-20 US claimed
WO-2016047988-A1 SURFACE MODIFIED BORON NITRIDE, COMPOSITION HAVING SAME DISPERSED THEREIN, AND WIRE COATED WITH THE COMPOSITION 세종대학교산학협력단 2016-03-31 WO disclosed
US-8927630-B2 Inorganic nanofiller, partial discharge resistant enameled wire including the same, and preparing method of the enameled wire SEJONG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2015-01-06 US disclosed
US-20130153263-A1 INORGANIC NANOFILLER, PARTIAL DISCHARGE RESISTANT ENAMELED WIRE INCLUDING THE SAME, AND PREPARING METHOD OF THE ENAMELED WIRE SEJONG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2013-06-20 US disclosed
US-20050118742-A1 Method for reducing the adhesive properties of MEMS and anti-adhesion-coated device ROBERT BOSCH GMBH (DE) 2005-06-02 US disclosed
US-6022987-A Aryl substituted alkylsilanes and a preparation method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2000-02-08 US disclosed