Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10915412 | 0.96 | MEN1 (0.50) | CA1CA2CA9MEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL27241852 | 0.92 | MEN1 (0.47) | CA1CA2CA9MEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL5024687 | 0.91 | CA1 (0.46) | CA1CA2CA9MEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL9216046 | 0.91 | CA1 (0.46) | CA1CA2CA9MEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL28194868 | 0.91 | CA1 (0.46) | CA1CA2CA9MEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL11062955 | 0.91 | MEN1 (0.54) | CA1CA2CA9MEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL5822498 | 0.91 | CA1 (0.46) | CA1CA2CA9MEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL4535186 | 0.91 | CA1 (0.46) | CA1CA2CA9MEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL8005830 | 0.91 | CA1 (0.46) | CA1CA2CA9MEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL1931202 | 0.91 | MEN1 (0.54) | CA1CA2CA9MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105964681-B | Method for improving soil cadmium removal capability of tobacco by use of fertilization and harvesting technology | 湖南农业大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-104704050-B | The preparation method of polylactic acid resin composition, molded body and polylactic acid resin composition | 东丽株式会社 | 2016-10-12 | — | — | CN | disclosed |
| CN-105964681-A | Method for improving soil cadmium removal capability of tobacco by use of fertilization and harvesting technology | 湖南农业大学 | 2016-09-28 | — | — | CN | disclosed |
| US-6943182-B2 | Cyclopentabenzofuran derivatives and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2005-09-13 | — | — | US | disclosed |
| US-20030144334-A1 | Cyclopentabenzofuran derivatives and their use | GUARNIERI WALTER (DE) | 2003-07-31 | — | — | US | disclosed |
| US-6420393-B1 | NUCLEAR FACTOR .KAPPA.B-DEPENDENT DISEASE SELECTED FROM THE GROUP CONSISTING OF INFLAMMATORY DISEASES, IMMUNOLOGICAL DISORDERS, SEPTIC SHOCK, TRANSPLANT REJECTION, RADIATION DAMAGE, REPERFUSION INJURIES AFTER ISCHEMIA, STROKE OR | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| US-RE37035-E1 | HYPOGLYCEMIC AGENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-01-30 | — | — | US | disclosed |
| US-6143769-A | ENANTIOMORPH | KARL THOMAE GMBH (DE) | 2000-11-07 | — | — | US | disclosed |
| US-5312924-A | Compounds for lowering blood sugar and effecting metabolism | DR. KARL THOMAE GMBH (DE) | 1994-05-17 | — | — | US | disclosed |
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | disclosed |
| US-5216167-A | Hypoglycemic agents | DR. KARL THOMAE GMBH (DE) | 1993-06-01 | — | — | US | disclosed |
| US-4966836-A | QUATERNARY HETEROCYCLIC NUCLEATING AGENT WITH HETEROCYCLIC ACCELERATOR, GOOD DENSITIES | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| US-4945033-A | Direct positive photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1990-07-31 | — | — | US | disclosed |
| US-4876393-A | CHEMICAL INTERMEDIATES FOR BIOLOGICALLY ACTIVE COMPOUNDS; INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-24 | — | — | US | disclosed |
| US-4021446-A | 4-Benzyloxymethyl-5-[(1-pyrrolidinyl-carbonyl)-methyl]-1,3-cyclopentylene-diacetate compounds | HOFFMANN-LA ROCHE INC. (US) | 1977-05-03 | — | — | US | disclosed |
| US-4011335-A | INSECTICIDES, HORMONE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144334-A1 | Cyclopentabenzofuran derivatives and their use | NFKBIA, IKBKG, NFKB1 | CA1 4578/4885CA2 3141/4885CA9 4090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.