Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.69 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.69 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.63 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325147 | 1.00 | CHRNB2 (0.69) | CHRNB2CHRNA4CHRNA7CHRNA1LMNA | |
| SCHEMBL8184788 | 0.85 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA7CHRNA1LMNA | |
| Thiacloprid Olefin SCHEMBL7735960 | 0.82 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7CHRNA1LMNA | |
| SCHEMBL6325960 | 0.81 | CHRNB2 (0.65) | CHRNB2CHRNA4CHRNA7CHRNA1LMNA | |
| SCHEMBL6325966 | 0.81 | CHRNB2 (0.65) | CHRNB2CHRNA4CHRNA7CHRNA1LMNA | |
| SCHEMBL9839961 | 0.80 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7CHRNA1LMNA | |
| SCHEMBL9839965 | 0.80 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7CHRNA1LMNA | |
| SCHEMBL7504331 | 0.77 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7CHRNA1LMNA | |
| SCHEMBL18059975 | 0.77 | CHRNB2 (0.60) | CHRNB2CHRNA4CHRNA7CHRNA1LMNA | |
| SCHEMBL10684735 | 0.77 | CHRNB2 (0.60) | CHRNB2CHRNA4CHRNA7CHRNA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078259-A1 | Di-substituted imineheterocyclic compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2003-04-24 | — | — | US | claimed |
| US-6900202-B2 | Di-substituted imineheterocyclic compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20030078259-A1 | Di-substituted imineheterocyclic compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078259-A1 | Di-substituted imineheterocyclic compounds | CHRNA2, CHRNA7, CHRNB2 | CHRNB2 3/4885CHRNA4 15/4885CHRNA7 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.