SCHEMBL6325368

SCHEMBL6325368

C=C(C)C(=O)Oc1c(OC)cc(C2(c3cc(OC)c(OC(=O)C(=C)C)c(CCC)c3OC)c3ccccc3-c3ccccc32)c(OC)c1CCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.36
FPR1 P21462 1/20 0.32
LMNA P02545 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
HTT P42858 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
TSHR P16473 1/20 0.31
ELANE P08246 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
HTR1A P08908 1/20 0.30
PDK2 Q15119 1/20 0.30
NR1I2 O75469 1/20 0.30
CHRM2 P08172 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
ADRA2B P18089 1/20 0.30
SLC6A4 P31645 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6323470 0.92 ALOX5 (0.33) ALOX5FPR1LMNATDP1HTT
SCHEMBL6323480 0.87 TSHR (0.33) TSHRELANEMAPTPDK2
SCHEMBL6324382 0.86 PDK2 (0.34) PDK2ADORA3
SCHEMBL6325063 0.86 ELANE (0.35) LMNAHTTSMN1; SMN2TSHRELANE
SCHEMBL6328607 0.85 ELANE (0.32) ELANE
SCHEMBL7072257 0.84 PDK2 (0.34) LMNAHTTSMN1; SMN2TSHRELANE
SCHEMBL6324793 0.78 PDK2 (0.34) SMN1; SMN2ELANEPDK2
SCHEMBL6328897 0.78 TSHR (0.34) TDP1SMN1; SMN2TSHRELANEMAPT
SCHEMBL6325333 0.78 ELANE (0.31) ELANEPDK2
SCHEMBL6322382 0.77 PDK2 (0.33) ELANEPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10611869-B2 Curable composition and cured product AGC Inc. (JP) 2020-04-07 US disclosed
US-20190218325-A1 CURABLE COMPOSITION AND CURED PRODUCT AGC Inc. (JP) 2019-07-18 US disclosed
US-20050185232-A1 Volume hologram recording photosensitive composition and its use NIPPON PAINT CO., LTD. (JP) 2005-08-25 US disclosed
US-20030096172-A1 Hologram recording material composition and hologram recording medium DAISO CO., LTD. (JP) 2003-05-22 US disclosed