SCHEMBL6325395

SCHEMBL6325395

CCCCOC(=O)c1ccc(NC(=O)NS(=O)(=O)c2ccccc2C)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.56
RECQL P46063 1/20 0.56
POLB P06746 2/20 0.54
MAPT P10636 3/20 0.53
KMT2A Q03164 3/20 0.53
HTT P42858 2/20 0.53
MEN1 O00255 2/20 0.53
GAA P10253 2/20 0.53
NPSR1 Q6W5P4 2/20 0.53
LMNA P02545 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
ALDH1A1 P00352 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
MAPK1 P28482 1/20 0.52
RAB9A P51151 3/20 0.49
CA12 O43570 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6725212 0.94 LMNA (0.53) HPGDRECQLPOLBMAPTKMT2A
SCHEMBL6732256 0.94 LMNA (0.53) HPGDRECQLPOLBMAPTKMT2A
SCHEMBL6724948 0.93 LMNA (0.54) HPGDMAPTKMT2AMEN1GAA
SCHEMBL6329425 0.89 SMN1; SMN2 (0.58) HPGDPOLBMAPTKMT2AHTT
SCHEMBL6732258 0.88 HPGD (0.55) HPGDRECQLPOLBMAPTKMT2A
SCHEMBL6323993 0.85 SMN1; SMN2 (0.53) HPGDPOLBMAPTKMT2AMEN1
SCHEMBL6326659 0.85 SMN1; SMN2 (0.53) HPGDPOLBMAPTKMT2AMEN1
SCHEMBL6331748 0.85 SMN1; SMN2 (0.53) HPGDPOLBMAPTKMT2AMEN1
SCHEMBL1931137 0.83 SMN1; SMN2 (0.50) HPGDPOLBMAPTKMT2AMEN1
SCHEMBL1931062 0.83 SMN1; SMN2 (0.50) HPGDPOLBMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
EP-1044824-B1 Bis(arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO (JP) 2004-05-12 EP disclosed
US-6677472-B2 AS COLOR-DEVELOPING AGENT; HIGH WHITENESS AND RESISTANCE TO COLOR FORMATION UNDER HIGH TEMPERATURE OJI PAPER CO., LTD. (JP) 2004-01-13 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed
US-6486094-B1 Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO., LTD. (JP) 2002-11-26 US disclosed
US-20020065196-A1 Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO., LTD. (JP) 2002-05-30 US disclosed
EP-1044824-A2 Bis(arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER COMPANY LIMITED (JP) 2000-10-18 EP disclosed