SCHEMBL6724948

SCHEMBL6724948

CCCOC(=O)c1ccc(NC(=O)NS(=O)(=O)c2ccccc2C)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.54
NPSR1 Q6W5P4 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
ALDH1A1 P00352 8/20 0.53
HPGD P15428 4/20 0.53
MAPT P10636 4/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
THRB P10828 1/20 0.53
RAB9A P51151 5/20 0.52
CA12 O43570 2/20 0.51
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA9 Q16790 2/20 0.51
SMN1; SMN2 Q16637 4/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6325395 0.93 HPGD (0.56) LMNANPSR1CYP1A2CYP3A4CYP2D6
SCHEMBL6732256 0.92 LMNA (0.53) LMNANPSR1CYP1A2CYP3A4CYP2D6
SCHEMBL6725212 0.92 LMNA (0.53) LMNANPSR1CYP1A2CYP3A4CYP2D6
SCHEMBL6331093 0.88 ALDH1A1 (0.58) LMNANPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL6725193 0.85 ALDH1A1 (0.59) LMNANPSR1ALDH1A1HPGDMAPT
SCHEMBL6727603 0.83 LMNA (0.48) LMNANPSR1CYP1A2CYP3A4CYP2D6
SCHEMBL6329425 0.82 SMN1; SMN2 (0.58) LMNANPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL6325376 0.81 CA2 (0.60) LMNAALDH1A1HPGDMAPTMEN1
SCHEMBL6732258 0.81 HPGD (0.55) CYP1A2CYP2C9CYP2C19ALDH1A1HPGD
SCHEMBL6326396 0.81 CA1 (0.52) HPGDMEN1KMT2ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1044824-B1 Bis(arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO (JP) 2004-05-12 EP disclosed
US-6677472-B2 AS COLOR-DEVELOPING AGENT; HIGH WHITENESS AND RESISTANCE TO COLOR FORMATION UNDER HIGH TEMPERATURE OJI PAPER CO., LTD. (JP) 2004-01-13 US disclosed
US-6486094-B1 Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO., LTD. (JP) 2002-11-26 US disclosed
US-20020065196-A1 Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO., LTD. (JP) 2002-05-30 US disclosed
EP-1044824-A2 Bis(arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER COMPANY LIMITED (JP) 2000-10-18 EP disclosed