Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599829 | 0.82 | KDM4E (0.41) | MEN1KMT2ATSHRNPSR1ALDH1A1 | |
| SCHEMBL6325457 | 0.80 | MRGPRX1 (0.41) | MEN1KMT2AMAPTTSHRMRGPRX1 | |
| SCHEMBL6331130 | 0.80 | MRGPRX1 (0.41) | MEN1KMT2ATSHRALDH1A1MRGPRX1 | |
| SCHEMBL6324376 | 0.78 | MRGPRX1 (0.43) | MEN1KMT2ANPSR1ALDH1A1RAB9A | |
| SCHEMBL6323916 | 0.77 | MRGPRX1 (0.40) | MEN1KMT2AALDH1A1MRGPRX1 | |
| SCHEMBL6330219 | 0.70 | MEN1 (0.36) | MEN1KMT2AL3MBTL1MAPTTSHR | |
| SCHEMBL6323776 | 0.70 | L3MBTL1 (0.42) | MEN1KMT2AL3MBTL1MAPTTSHR | |
| SCHEMBL6324447 | 0.70 | KMT2A (0.40) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL6321845 | 0.69 | KDM4E (0.43) | MEN1KMT2ATSHRNPSR1ALDH1A1 | |
| SCHEMBL20118984 | 0.68 | NPC1 (0.57) | MEN1KMT2AMAPK1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924284-B2 | PARP inhibitors | ICOS CORPORATION (US) | 2005-08-02 | — | — | US | disclosed |
| US-6858565-B2 | Thermosensitive recording material and novel color developer compounds | OJI PAPER CO., LTD. (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20030040434-A1 | Thermosensitive recording material and novel color developer compounds | OJI PAPER CO., LTD. (JP) | 2003-02-27 | — | — | US | disclosed |
| EP-1264707-A2 | Thermosensitive recording material and novel color developer compounds | OJI PAPER CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |