SCHEMBL6325457

SCHEMBL6325457

CCOP(=O)(OCC)c1ccccc1NC(=O)NS(=O)(=O)C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MRGPRX1 Q96LB2 9/20 0.41
KMT2A Q03164 4/20 0.40
POLB P06746 1/20 0.39
MEN1 O00255 3/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSPO P30536 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.35
LMNA P02545 1/20 0.35
FPR1 P21462 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6324376 0.92 MRGPRX1 (0.43) MRGPRX1KMT2APOLBMEN1HTT
SCHEMBL6323916 0.90 MRGPRX1 (0.40) MRGPRX1KMT2APOLBMEN1HTT
SCHEMBL7599829 0.88 KDM4E (0.41) MRGPRX1KMT2AMEN1HTTSMN1; SMN2
SCHEMBL6331130 0.85 MRGPRX1 (0.41) MRGPRX1KMT2AMEN1HTTSMN1; SMN2
SCHEMBL6325435 0.80 MEN1 (0.39) MRGPRX1KMT2AMEN1MAPTTSHR
SCHEMBL6324299 0.78 KMT2A (0.42) MRGPRX1KMT2APOLBMEN1HTT
SCHEMBL6324447 0.74 KMT2A (0.40) MRGPRX1KMT2AMEN1HTTSMN1; SMN2
SCHEMBL6326717 0.74 MRGPRX1 (0.42) MRGPRX1KMT2AMEN1HTTSMN1; SMN2
SCHEMBL6321845 0.74 KDM4E (0.43) MRGPRX1KMT2AMEN1HTTSMN1; SMN2
SCHEMBL6329861 0.72 KMT2A (0.39) MRGPRX1KMT2AMEN1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed