SCHEMBL6325510

SCHEMBL6325510

CC(C)(C)c1cc(-c2ccccc2-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
HSP90AA1 P07900 1/20 0.38
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
LMNA P02545 1/20 0.33
ALOX5 P09917 2/20 0.32
PTGS2 P35354 2/20 0.32
HSD11B1 P28845 1/20 0.31
POLB P06746 1/20 0.31
KDM4E B2RXH2 3/20 0.30
MAPT P10636 2/20 0.30
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
APAF1 O14727 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29349567 0.85 NPC1 (0.41) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL29241 0.85 NPC1 (0.41) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL11668139 0.83 NPC1 (0.43) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
Toluene SCHEMBL29114789 0.82 NPC1 (0.46) NPC1RAB9ACYP1A2CYP3A4CYP2C9
Bumetrizole SCHEMBL8250511 0.81 NPC1 (0.54) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL6325507 0.81 NPC1 (0.35) NPC1RAB9AHSP90AA1TSHRLMNA
SCHEMBL6325514 0.81 MAPT (0.41) NPC1RAB9AHSP90AA1POLBKDM4E
Pyrrole SCHEMBL28116614 0.81 NPC1 (0.39) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL23908723 0.81 NPC1 (0.38) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL22372500 0.81 NPC1 (0.44) NPC1RAB9AHSP90AA1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050191476-A1 Epoxy resin composition excellent in weather resistance and fiber-reinforced composite materials TORAY INDUSTRIES, INC. A CORPORATION OF JAPAN (JP) 2005-09-01 US disclosed
EP-1454956-A1 EPOXY RESIN COMPOSITION EXCELLENT IN WEATHER RESISTANCE AND FIBER-REINFORCED COMPOSITE MATERIALS TORAY INDUSTRIES, INC. (JP) 2004-09-08 EP disclosed