Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.60 |
| ▸ | ESR1 | P03372 | 4/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.59 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9765277 | 0.98 | TAAR1 (0.58) | TAAR1ESR1ESR2HTR3ATSHR | |
| SCHEMBL3006604 | 0.87 | TAAR1 (0.75) | TAAR1ESR1ESR2HTR3ATSHR | |
| Hydrochloric Acid SCHEMBL6564727 | 0.85 | TAAR1 (0.71) | TAAR1ESR1ESR2HTR3ATSHR | |
| SCHEMBL11464625 | 0.82 | ESR1 (0.55) | TAAR1ESR1ESR2HTR3ATSHR | |
| SCHEMBL6341136 | 0.80 | ESR1 (0.64) | TAAR1ESR1ESR2HTR3ATSHR | |
| Bromide SCHEMBL11287353 | 0.78 | CYP2C9 (0.44) | TAAR1ESR1ESR2HTR3ATSHR | |
| SCHEMBL548248 | 0.78 | ESR1 (0.61) | TAAR1ESR1ESR2HTR3ATSHR | |
| SCHEMBL19245695 | 0.78 | ESR1 (0.62) | ESR1ESR2TSHRALOX15TDP1 | |
| SCHEMBL20765447 | 0.78 | ESR1 (0.62) | ESR1ESR2TSHRALOX15TDP1 | |
| SCHEMBL85692 | 0.78 | ESR1 (0.62) | ESR1ESR2TSHRALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234917-A1 | ASPARAGINE DERIVATIVES AND METHODS OF USING SAME | SENDA BIOSCIENCES INC (US) | 2023-07-27 | — | — | US | disclosed |
| US-20230234917-A1 | ASPARAGINE DERIVATIVES AND METHODS OF USING SAME | SENDA BIOSCIENCES INC (US) | 2023-07-27 | — | — | US | disclosed |
| WO-2021252640-A1 | ASPARAGINE DERIVATIVES AND METHODS OF USING SAME | SENDA BIOSCIENCES, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
| US-20210206727-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | UNIV OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2021-07-08 | — | — | US | disclosed |
| CN-106995410-B | Lactam derivative and application thereof | 江苏恩华药业股份有限公司 | 2021-03-02 | — | — | CN | disclosed |
| US-10766866-B2 | Deterrents for arthropods and marine organisms | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2020-09-08 | — | — | US | disclosed |
| US-20190292156-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH | 2019-09-26 | — | — | US | disclosed |
| CN-106995410-A | A kind of lactam derivative and its application | 江苏恩华药业股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| WO-2013147286-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD, EACH USING THE SAME | FUJIFILM CORPORATION (JP) | 2013-10-03 | — | — | WO | disclosed |
| EP-1866357-B1 | (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF | SHOWA DENKO KK (JP) | 2012-02-22 | — | — | EP | disclosed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007008603-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |
| WO-2006103979-A1 | (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF | SHOWA DENKO K.K. (JP) | 2006-10-05 | — | — | WO | disclosed |
| EP-0253340-B1 | ALKYL-SUBSTITUTED BENZOXAZINORIFAMYCIN DERIVATIVE, PROCESS FOR PREPARING THE SAME AND ANTIBACTERIAL AGENT CONTAINING THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4859661-A | Alkyl-substituted benzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-08-22 | — | — | US | disclosed |
| US-4843160-A | Preparation of alpha-aminoalkylphenols | THE DOW CHEMICAL COMPANY (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0253340-A1 | Alkyl-substituted benzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766866-B2 | Deterrents for arthropods and marine organisms | ALG1, NISCH, ALG8 | TAAR1 351/4885ESR1 4132/4885ESR2 3900/4885 |
| US-20210206727-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | ALG1, ALG8, DDT | TAAR1 333/4885ESR1 4105/4885ESR2 3914/4885 |
| US-20230234917-A1 | ASPARAGINE DERIVATIVES AND METHODS OF USING SAME | ASNS, SI, NARS1 | TAAR1 4825/4885ESR1 4124/4885ESR2 4283/4885 |
| US-20190292156-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | ALG1, NISCH, ALG8 | TAAR1 351/4885ESR1 4132/4885ESR2 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.