Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3646429 | 0.67 | MEN1 (0.48) | MEN1CYP2C9KMT2A | |
| SCHEMBL6130805 | 0.65 | — | — | |
| SCHEMBL9660132 | 0.63 | ALDH1A1 (0.33) | — | |
| SCHEMBL6219210 | 0.63 | MEN1 (0.30) | MEN1CYP2C9KMT2A | |
| SCHEMBL12920580 | 0.63 | KMT2A (0.48) | MEN1CYP2C9KMT2A | |
| SCHEMBL9629481 | 0.62 | — | — | |
| SCHEMBL992137 | 0.62 | — | — | |
| SCHEMBL17113652 | 0.62 | TRIM24 (0.36) | — | |
| SCHEMBL11023410 | 0.62 | ALDH1A1 (0.30) | — | |
| SCHEMBL2002992 | 0.62 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841671-B2 | Spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors | PFIZER INC. (US) | 2005-01-11 | — | — | US | disclosed |