Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326000 | 0.78 | HRH3 (0.43) | GAALMNAPOLBHRH3GPR183 | |
| SCHEMBL28765618 | 0.75 | CHRM2 (0.41) | GAALMNAPOLBGPR183ALDH1A1 | |
| SCHEMBL16227288 | 0.70 | ACHE (0.59) | GAALMNACYP3A4MEN1KMT2A | |
| SCHEMBL457537 | 0.70 | GAA (0.36) | GAAALDH1A1EPHX2 | |
| SCHEMBL27577404 | 0.67 | HRH3 (0.42) | HRH3ALDH1A1PKMMC4R | |
| SCHEMBL22252719 | 0.67 | POLB (0.56) | POLBCYP3A4ALDH1A1CYP3A5L3MBTL1 | |
| SCHEMBL6325994 | 0.66 | RAD52 (0.46) | GAALMNAHRH3MMP13MMP14 | |
| SCHEMBL27794125 | 0.66 | CACNA1B (0.42) | GAAPOLBALDH1A1PKML3MBTL1 | |
| SCHEMBL26203636 | 0.66 | LMNA (0.47) | GAALMNAHRH3CYP3A4ALDH1A1 | |
| SCHEMBL25442196 | 0.64 | LMNA (0.73) | GAALMNAPOLBHRH3GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |