SCHEMBL63260

SCHEMBL63260

COc1ccc(NC(=O)N(C)C)cc1Cl

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.69
SMN1; SMN2 Q16637 5/20 0.61
HPGD P15428 2/20 0.61
TP53 P04637 1/20 0.61
PKM P14618 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
ALDH1A1 P00352 7/20 0.59
HTT P42858 2/20 0.59
MEN1 O00255 1/20 0.59
GLA P06280 1/20 0.59
KMT2A Q03164 1/20 0.59
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
POLB P06746 1/20 0.58
MAPT P10636 2/20 0.57
LMNA P02545 1/20 0.57
GRM4 Q14833 1/20 0.57
TSHR P16473 1/20 0.56
ACHE P22303 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8536442 1.00 APEX1 (0.69) APEX1SMN1; SMN2HPGDTP53PKM
SCHEMBL29776921 1.00 APEX1 (0.69) APEX1SMN1; SMN2HPGDTP53PKM
Chlorotoluron SCHEMBL10874615 0.93 APEX1 (0.60) APEX1SMN1; SMN2HPGDTP53PKM
Pentachlorophenol SCHEMBL21223139 0.92 APEX1 (0.58) APEX1SMN1; SMN2HPGDTP53PKM
SCHEMBL10671104 0.88 MEN1 (0.70) APEX1SMN1; SMN2HPGDTP53PKM
SCHEMBL11177802 0.86 APEX1 (0.58) APEX1SMN1; SMN2HPGDTP53PKM
SCHEMBL11759391 0.85 HTT (0.61) SMN1; SMN2HPGDTP53PKMNPSR1
SCHEMBL132331 0.84 RORC (0.72) APEX1SMN1; SMN2HPGDTP53ALDH1A1
SCHEMBL6696914 0.84 HTT (0.63) SMN1; SMN2HPGDTP53PKMNPSR1
SCHEMBL11163646 0.83 PNLIP (0.55) APEX1SMN1; SMN2NPSR1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14083 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260096553-A1 MICROENCAPSULATED HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2026-04-09 US claimed
US-20260092926-A1 BIOLOGICAL STATUS CLASSIFICATION RANDOX LABORATORIES LTD (GB) 2026-04-02 US claimed
US-20260060254-A1 HERBICIDAL COMPOSITIONS BAYER AG (DE) 2026-03-05 US claimed
US-12550896-B2 Early applications of encapsulated acetamides for reduced injury in crops MONSANTO TECHNOLOGY LLC (US) 2026-02-17 US claimed
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2026-01-08 US claimed
EP-4665151-A1 HERBICIDAL MIXTURES Bayer Aktiengesellschaft (DE) 2025-12-24 EP claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
US-20250318528-A1 HERBICIDE COMPOSITION AND WEED CONTROLLING METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-10-16 US claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-0043802-B1 SYNERGISTIC AGENTS AND METHOD FOR THE SELECTIVE CONTROL OF WEEDS, PARTICULARLY IN CEREALS CIBA-GEIGY AG (CH) 1984-02-22 EP claimed
EP-0052825-A1 Selective herbicidal agents on the basis of triazine diones BAYER AG (DE) 1982-06-02 EP claimed
EP-0013636-B1 HERBICIDAL COMPOSITIONS CONTAINING 2,4-DIAMINO-6-CHLORO-5-METHYLTHIO-PYRIMIDINE AND HERBICIDAL UREA DERIVATIVES AND METHOD OF TREATMENT OF CULTURES WITH SAID COMPOSITIONS P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1982-02-24 EP claimed
EP-0036244-A1 Herbicidal compositions comprising 1-(3,4-dichloro-benzyl)imidazole-N,N'-dimethyl-4,5-dicarboxamide MAY & BAKER LIMITED (GB) 1981-09-23 EP claimed
WO-1981000665-A1 PLANT PHYSIOLOGICALLY ACTIVE COMPOSITION AND USE FISONS LTD (GB) 1981-03-19 WO claimed
EP-0024841-A1 Plant physiologically active composition and use FBC LIMITED (GB) 1981-03-11 EP claimed
EP-0013636-A1 Herbicidal compositions containing 2,4-diamino-6-chloro-5-methylthio-pyrimidine and herbicidal urea derivatives and method of treatment of cultures with said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1980-07-23 EP claimed
EP-0006681-A1 Herbicidal composition and method FISONS plc (GB) 1980-01-09 EP claimed
US-3994714-A N-(3-CHLORO-4-METHOXYPHENYL)-N*,N*-DIMETHYLUREA SANDOZ LTD. (CH) 1976-11-30 US claimed
US-3989508-A Substituted nitroanilines and ureas as herbicidal mixtures BASF AKTIENGESELLSCHAFT (DT) 1976-11-02 US claimed