SCHEMBL6326155

SCHEMBL6326155

NC(=O)c1cccc(N(C(N)=O)S(=O)(=O)c2ccc(Cl)cc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
PARP1 P09874 1/20 0.47
RORC P51449 2/20 0.46
TP53 P04637 4/20 0.45
MAPT P10636 3/20 0.45
KDM4E B2RXH2 1/20 0.44
THRB P10828 1/20 0.42
CHEK2 O96017 1/20 0.42
FLT1 P17948 1/20 0.41
FLT4 P35916 1/20 0.41
KDR P35968 1/20 0.41
CYP3A4 P08684 1/20 0.40
CYP3A5 P20815 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6324423 0.87 KMT2A (0.46) LMNAPARP1TP53MAPTCYP3A4
SCHEMBL6326721 0.86 TP53 (0.53) LMNAPARP1RORCTP53MAPT
SCHEMBL6321902 0.83 LMNA (0.54) LMNATP53MAPTKDM4ETHRB
SCHEMBL6323766 0.80 PARP1 (0.54) LMNAPARP1RORCTP53MAPT
SCHEMBL6329886 0.80 PARP1 (0.43) LMNAPARP1RORCTP53MAPT
SCHEMBL6323524 0.76 TP53 (0.52) LMNAPARP1RORCTP53MAPT
SCHEMBL9068781 0.76 TP53 (0.58) LMNATP53MAPTKDM4ETHRB
SCHEMBL6241748 0.76 LMNA (0.55) LMNATP53MAPTKDM4ETHRB
SCHEMBL6326502 0.75 PARP1 (0.43) PARP1TP53MAPTCYP3A4KMT2A
SCHEMBL7999295 0.74 LMNA (0.76) LMNATP53MAPTKDM4ETHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed