SCHEMBL6324423

SCHEMBL6324423

NC(=O)c1cccc(N(C(N)=O)S(=O)(=O)c2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.46
AKR1C3 P42330 1/20 0.46
MAPT P10636 2/20 0.43
TP53 P04637 1/20 0.43
PARP1 P09874 6/20 0.43
LMNA P02545 3/20 0.43
POLB P06746 1/20 0.43
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSD11B1 P28845 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6326155 0.87 LMNA (0.55) KMT2AMAPTTP53PARP1LMNA
SCHEMBL6326721 0.87 TP53 (0.53) KMT2AMAPTTP53PARP1LMNA
SCHEMBL6323766 0.86 PARP1 (0.54) MAPTTP53PARP1LMNAHTT
SCHEMBL174224 0.84 KMT2A (0.62) KMT2AMAPTTSHRHSD11B1ALDH1A1
SCHEMBL6326502 0.81 PARP1 (0.43) KMT2AAKR1C3MAPTTP53PARP1
SCHEMBL6329886 0.81 PARP1 (0.43) KMT2AMAPTTP53PARP1LMNA
SCHEMBL7597834 0.80 LMNA (0.51) KMT2AMAPTLMNATDP1L3MBTL1
SCHEMBL1967123 0.78 LMNA (0.68) KMT2AMAPTLMNAL3MBTL1HTT
SCHEMBL28230825 0.77 CA12 (0.48) KMT2AMAPTTP53LMNAPOLB
SCHEMBL6323524 0.77 TP53 (0.52) KMT2AMAPTTP53PARP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed