SCHEMBL6327323

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7259547	0.96	GRIN1 (0.40)	GRIN1GRIN2BDRD2DRD4DRD3
	SCHEMBL6334766	0.89	DRD4 (0.44)	DRD2DRD4DRD3KCNH2CACNA1I
	SCHEMBL6328290	0.84	HRH1 (0.44)	DRD2DRD4DRD3KCNH2HTR4
	SCHEMBL6329782	0.81	NR4A2 (0.41)	KCNH2CACNA1IHTR4
	SCHEMBL6329269	0.81	DRD2 (0.58)	DRD2DRD4DRD3HTR4HDAC3
	SCHEMBL6334076	0.81	KCNH2 (0.43)	DRD2DRD4DRD3KCNH2CACNA1I
	SCHEMBL6335710	0.80	KCNH2 (0.60)	DRD2DRD4DRD3KCNH2CACNA1I
	SCHEMBL7259549	0.80	KCNH2 (0.43)	GRIN1GRIN2BDRD2DRD4DRD3
	SCHEMBL6329738	0.79	KCNH2 (0.43)	DRD2DRD4DRD3KCNH2CACNA1I
	SCHEMBL6327265	0.79	DRD2 (0.51)	DRD2DRD4DRD3KCNH2HTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.