Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.65 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327793 | 1.00 | CHRNA7 (0.71) | CHRNA7MEN1KMT2ATDP1CHRNA1 | |
| SCHEMBL9889726 | 1.00 | CHRNA7 (0.71) | CHRNA7MEN1KMT2ATDP1CHRNA1 | |
| SCHEMBL14606326 | 0.88 | CHRNA7 (0.73) | CHRNA7MEN1KMT2ATDP1CHRNA1 | |
| SCHEMBL6324205 | 0.86 | CHRNA7 (0.71) | CHRNA7MEN1KMT2ATDP1CHRNA1 | |
| SCHEMBL13283613 | 0.86 | CHRNA7 (0.71) | CHRNA7MEN1KMT2ATDP1CHRNA1 | |
| SCHEMBL13516536 | 0.86 | CHRNA7 (0.71) | CHRNA7MEN1KMT2ATDP1CHRNA1 | |
| SCHEMBL13516537 | 0.86 | CHRNA7 (0.71) | CHRNA7MEN1KMT2ATDP1CHRNA1 | |
| SCHEMBL6324210 | 0.86 | CHRNA7 (0.71) | CHRNA7MEN1KMT2ATDP1CHRNA1 | |
| SCHEMBL6325078 | 0.84 | CHRNA7 (0.68) | CHRNA7MEN1KMT2ATDP1CHRNA1 | |
| SCHEMBL6325074 | 0.84 | CHRNA7 (0.68) | CHRNA7MEN1KMT2ATDP1CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078259-A1 | Di-substituted imineheterocyclic compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2003-04-24 | — | — | US | claimed |
| EP-1218371-A2 | DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS | SUNTORY LIMITED (JP) | 2002-07-03 | — | — | EP | claimed |
| WO-2001070733-A2 | DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS | SUNTORY LIMITED (JP) | 2001-09-27 | — | — | WO | claimed |
| US-6900202-B2 | Di-substituted imineheterocyclic compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20030078259-A1 | Di-substituted imineheterocyclic compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1218371-A2 | DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS | SUNTORY LIMITED (JP) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001070733-A2 | DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS | SUNTORY LIMITED (JP) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078259-A1 | Di-substituted imineheterocyclic compounds | CHRNA2, CHRNA7, CHRNB2 | CHRNA7 2/4885MEN1 2653/4885KMT2A 2524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.