Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 19/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 16/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492915 | 0.86 | OPRD1 (0.76) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5490000 | 0.85 | OPRD1 (0.62) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5485781 | 0.83 | OPRD1 (0.60) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7248855 | 0.81 | OPRD1 (0.64) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6337054 | 0.79 | OPRD1 (0.66) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6334466 | 0.78 | OPRD1 (0.65) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6393279 | 0.78 | OPRD1 (0.87) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6176767 | 0.77 | OPRD1 (1.00) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6332701 | 0.76 | OPRD1 (0.85) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6334645 | 0.76 | OPRD1 (0.85) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875777-B2 | Compounds | ASTRAZENECA AB (SE) | 2005-04-05 | — | — | US | disclosed |
| EP-1242406-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-03-17 | — | — | EP | disclosed |