SCHEMBL6327852

SCHEMBL6327852

C(=P(c1ccccc1)(c1ccccc1)c1ccccc1)=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA5A P35218 1/20 0.41
HTT P42858 2/20 0.37
ESR1 P03372 3/20 0.36
ESR2 Q92731 2/20 0.36
CFTR P13569 1/20 0.36
LMNA P02545 1/20 0.35
APP P05067 1/20 0.35
ALDH1A1 P00352 4/20 0.35
GAA P10253 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALOX12 P18054 2/20 0.35
MAPT P10636 1/20 0.35
ALPG P10696 1/20 0.35
NPY1R P25929 1/20 0.35
NPY2R P49146 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TSHR P16473 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19158852 0.75 CA2 (0.38) CA2CA4CA5AHTTESR1
SCHEMBL564408 0.75 CA2 (0.43) CA2CA4CA5AHTTESR1
SCHEMBL3957389 0.73 CA2 (0.42) CA2CA4CA5AHTTESR1
SCHEMBL15397878 0.73 CA2 (0.42) CA2CA4CA5AHTTESR1
SCHEMBL29609286 0.73 CA2 (0.42) CA2CA4CA5AHTTESR1
Hydrochloric Acid SCHEMBL10713177 0.71 CA2 (0.40) CA2CA4CA5AHTTESR1
SCHEMBL7435006 0.71 CA2 (0.40) CA2CA4CA5AHTTESR1
SCHEMBL99519 0.69 CA2 (0.43) CA2CA4CA5AHTTESR1
SCHEMBL10712482 0.68 CA2 (0.37) CA2CA4CA5AHTTESR1
SCHEMBL2932036 0.67 CA2 (0.47) CA2CA4CA5AHTTESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050080215-A1 Method for preparing polyorganosiloxanes (pos) by polycondensation/redistribution of oligosiloxanes in the presence of a strong base and strong bases used RHODIA CHIMIE (FR) 2005-04-14 US disclosed
EP-1453887-A1 METHOD FOR PREPARING POLYORGANOSILOXANES (POS) BY POLYCONDENSATON/REDISTRIBUTION OF OLIGOSILOXANES IN THE PRESENCE OF A STRONG BASE AND STRONG BASES USED RHODIA CHIMIE (FR) 2004-09-08 EP disclosed
WO-2003054058-A1 METHOD FOR PREPARING POLYORGANOSILOXANES (POS) BY POLYCONDENSATON/REDISTRIBUTION OF OLIGOSILOXANES IN THE PRESENCE OF A STRONG BASE AND STRONG BASES USED RHODIA CHIMIE (FR) 2003-07-03 WO disclosed