SCHEMBL7435006

SCHEMBL7435006

O=C=C=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA5A P35218 1/20 0.40
CFTR P13569 1/20 0.36
ALDH1A1 P00352 6/20 0.34
GAA P10253 3/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
HTT P42858 2/20 0.34
MAPT P10636 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALPG P10696 1/20 0.34
ALOX12 P18054 1/20 0.34
NPY1R P25929 1/20 0.34
NPY2R P49146 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TSHR P16473 3/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
ALOX15 P16050 1/20 0.33
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564408 0.78 CA2 (0.43) CA2CA4CA5ACFTRALDH1A1
SCHEMBL3957389 0.76 CA2 (0.42) CA2CA4CA5ACFTRALDH1A1
SCHEMBL28087904 0.76 CA2 (0.42) CA2CA4CA5ACFTRALDH1A1
SCHEMBL29609286 0.76 CA2 (0.42) CA2CA4CA5ACFTRALDH1A1
SCHEMBL15397878 0.76 CA2 (0.42) CA2CA4CA5ACFTRALDH1A1
Hydrochloric Acid SCHEMBL10713177 0.74 CA2 (0.40) CA2CA4CA5ACFTRALDH1A1
SCHEMBL6327852 0.71 CA2 (0.41) CA2CA4CA5ACFTRALDH1A1
SCHEMBL10712482 0.70 CA2 (0.37) CA2CA4CA5ACFTRALDH1A1
Acetic Acid SCHEMBL19208997 0.69 KMT2A (0.41) CA2CA4CA5ACFTRALDH1A1
SCHEMBL9466535 0.67 MIF (0.43) CA2CA4CA5AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220115694-A1 LITHIUM ION BATTERIES WITH HIGH VOLTAGE ELECTROLYTE ADDITIVES WILDCAT DISCOVERY TECHNOLOGIES, INC 2022-04-14 US claimed
EP-4647427-A1 COMPOUND FOR PREVENTING AND/OR TREATING NEURODEGENERATIVE DISEASE TYK Medicines, Inc. (CN) 2025-11-12 EP disclosed
US-11850230-B2 Composition for preventing or treating TNF-related diseases, containing novel derivative as active ingredient, and method for inhibiting TNF activity by using same ILAB (KR) 2023-12-26 US disclosed
US-20230099574-A1 COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING NOVEL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME ILAB (KR) 2023-03-30 US disclosed
US-20220115694-A1 LITHIUM ION BATTERIES WITH HIGH VOLTAGE ELECTROLYTE ADDITIVES WILDCAT DISCOVERY TECHNOLOGIES, INC 2022-04-14 US disclosed
EP-3699174-A1 COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING NOVEL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME ILAB (KR) 2020-08-26 EP disclosed
US-20200246304-A1 Composition For Preventing Or Treating TNF-Related Diseases, Containing Novel Derivative As Active Ingredient, And Method For Inhibiting TNF Activity By Using Same ILAB (KR) 2020-08-06 US disclosed
US-20190217268-A1 CHEMICAL REACTION DEVICE, AND METHOD FOR PRODUCING SAME NEC CORPORATION (JP) 2019-07-18 US disclosed
US-10119972-B2 Reactive labelling compounds and uses thereof ACADEMIA SINICA (TW) 2018-11-06 US disclosed
US-10011589-B2 Treatments for gastrointestinal conditions BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2018-07-03 US disclosed
EP-0866801-A1 CYCLOPEPTOLIDES Novartis AG (CH) 1998-09-30 EP disclosed
EP-0793656-A1 NOVEL BENZYL PYRIMIDINES F. HOFFMANN-LA ROCHE AG (CH) 1997-09-10 EP disclosed
WO-1997019104-A1 CYCLOPEPTOLIDES NOVARTIS AG (CH) 1997-05-29 WO disclosed
WO-1996016046-A2 NOVEL BENZYL PYRIMIDINES F. HOFFMANN-LA ROCHE AG (CH) 1996-05-30 WO disclosed
EP-0482100-A1 NOVEL VITAMIN D ANALOGUES. LEO PHARM PROD LTD (DK) 1992-04-29 EP disclosed
EP-0479871-A1 NOVEL VITAMIN D ANALOGUES. LEO PHARM PROD LTD (DK) 1992-04-15 EP disclosed
WO-1991000271-A1 NOVEL VITAMIN D ANALOGUES Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) 1991-01-10 WO disclosed
EP-0174858-A1 Isoindolinone derivatives, production and use thereof Takeda Chemical Industries, Ltd. (JP) 1986-03-19 EP disclosed
EP-0050534-A1 Esters of cyclopropane-carboxylic acids related to pyrethric acid, their preparation and use as insecticides ROUSSEL-UCLAF (FR) 1982-04-28 EP disclosed
US-4324902-A 7-[5-Oxo-3-hydroxy-2-(3-substituted)-3-hydroxypropyl)-1-cyclopentene]-heptanoic acids and derivatives thereof G. D. SEARLE & CO. (US) 1982-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10011589-B2 Treatments for gastrointestinal conditions SI, FABP2, SLC10A2 CA2 681/4885CA4 445/4885CA5A 171/4885
US-11850230-B2 Composition for preventing or treating TNF-related diseases, containing novel derivative as active ingredient, and method for inhibiting TNF activity by using same TNF, NFKBIA, TRAF6 CA2 2558/4885CA4 2600/4885CA5A 4421/4885
US-20230099574-A1 COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING NOVEL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME TNF, NFKBIA, TRAF6 CA2 2558/4885CA4 2600/4885CA5A 4421/4885
US-10119972-B2 Reactive labelling compounds and uses thereof MPI, AADAC, PAICS CA2 3647/4885CA4 760/4885CA5A 309/4885
US-20200246304-A1 Composition For Preventing Or Treating TNF-Related Diseases, Containing Novel Derivative As Active Ingredient, And Method For Inhibiting TNF Activity By Using Same TNF, NFKBIA, TRAF6 CA2 2558/4885CA4 2600/4885CA5A 4421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.