Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | METAP1 | P53582 | 2/20 | 0.73 |
| ▸ | GSK3B | P49841 | 8/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CLK1 | P49759 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.61 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328220 | 1.00 | MAPT (1.00) | MAPTLMNARAB9AMETAP1GSK3B | |
| SCHEMBL12821679 | 0.85 | GSK3B (0.81) | MAPTLMNARAB9AMETAP1GSK3B | |
| SCHEMBL12821680 | 0.85 | GSK3B (0.81) | MAPTLMNARAB9AMETAP1GSK3B | |
| SCHEMBL4096609 | 0.84 | METAP1 (1.00) | MAPTLMNARAB9AMETAP1MEN1 | |
| SCHEMBL24991965 | 0.83 | MAPT (0.71) | MAPTLMNARAB9AMETAP1GSK3B | |
| SCHEMBL15319819 | 0.83 | MAPT (0.71) | MAPTLMNARAB9AMETAP1GSK3B | |
| SCHEMBL8218253 | 0.82 | GSK3B (1.00) | MAPTLMNARAB9AMETAP1GSK3B | |
| SCHEMBL16685430 | 0.82 | GSK3B (1.00) | MAPTLMNARAB9AMETAP1GSK3B | |
| SCHEMBL16685431 | 0.82 | GSK3B (1.00) | MAPTLMNARAB9AMETAP1GSK3B | |
| SCHEMBL10750988 | 0.80 | GSK3B (0.68) | MAPTLMNARAB9AGSK3BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6926922-B2 | PWB manufacture | SHIPLEY COMPANY, L.L.C. (US) | 2005-08-09 | — | — | US | disclosed |
| US-20040022934-A1 | PWB manufacture | SHIPLEY COMPANY, L.L.C. (US) | 2004-02-05 | — | — | US | disclosed |
| EP-1353539-A2 | PWB manufacture | Shipley Co. L.L.C. (US) | 2003-10-15 | — | — | EP | disclosed |
| US-3932449-A | 5-(P-dimethylaminobenzyl) hydantoin | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-01-13 | — | — | US | disclosed |