SCHEMBL4096609

SCHEMBL4096609

CN(C)c1ccc(C=C2C(=O)NC(=O)NC2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 7/20 1.00
MAPT P10636 7/20 0.73
LMNA P02545 2/20 0.73
RAB9A P51151 2/20 0.73
APP P05067 5/20 0.63
SNCA P37840 4/20 0.63
ALDH1A1 P00352 4/20 0.63
PDGFRB P09619 3/20 0.63
MEN1 O00255 2/20 0.63
MAPK1 P28482 2/20 0.63
KMT2A Q03164 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
NPC1 O15118 1/20 0.63
GMNN O75496 1/20 0.63
HPGD P15428 1/20 0.63
MTOR P42345 1/20 0.63
BLM P54132 1/20 0.63
PMP22 Q01453 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29711922 0.93 METAP1 (0.86) METAP1MAPTLMNARAB9AAPP
SCHEMBL4037782 0.86 METAP1 (0.76) METAP1MAPTLMNARAB9AAPP
SCHEMBL4428107 0.84 METAP1 (0.80) METAP1MAPTALDH1A1KMT2ACA12
SCHEMBL6328218 0.84 MAPT (1.00) METAP1MAPTLMNARAB9AAPP
SCHEMBL6328220 0.84 MAPT (1.00) METAP1MAPTLMNARAB9AAPP
SCHEMBL10095181 0.81 MEN1 (0.78) METAP1MAPTLMNAALDH1A1MEN1
SCHEMBL16543003 0.80 METAP1 (1.00) METAP1MAPTLMNARAB9AAPP
SCHEMBL16712247 0.80 METAP1 (0.66) METAP1MAPTLMNARAB9AALDH1A1
SCHEMBL28680183 0.79 METAP1 (0.67) METAP1MAPTRAB9AALDH1A1MEN1
SCHEMBL10134144 0.79 METAP1 (0.66) METAP1MAPTLMNARAB9AAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2486115-B1 ELECTRORHEOLOGIC FLUID COMPRISING ORGANIC SUBSTANCES THAT CAN BE DOPED AND USE THEREOF FRAUNHOFER GES FORSCHUNG (DE) 2015-05-20 EP claimed
WO-2004059604-A2 METHOD AND SYSTEM FOR FABRICATING AN OLED HONEYWELL INTERNATIONAL, INC. (US) 2004-07-15 WO claimed
US-20040132228-A1 Method and system for fabricating an OLED HONEYWELL INTERNATIONAL INC. (US) 2004-07-08 US claimed
US-4707297-A Removable guidepath for automated guidance vehicles BELL & HOWELL COMPANY (US) 1987-11-17 US claimed
US-20220017474-A1 Novel Polycyclic Compound EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2022-01-20 US disclosed
EP-3896067-A1 NOVEL POLYCYCLIC COMPOUND Eutec New Materials Technology (Suzhou) Co., Ltd (CN) 2021-10-20 EP disclosed
WO-2020118933-A1 NOVEL POLYCYCLIC COMPOUND 优缔新材料科技(苏州)有限公司 2020-06-18 WO disclosed
US-8822109-B2 Colored curable composition, color filter, and solid image pickup element FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-8822109-B2 Colored curable composition, color filter, and solid image pickup element FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-8303860-B2 Colored curable composition, color filter and solid-state imaging device FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-8303860-B2 Colored curable composition, color filter and solid-state imaging device FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-8252490-B2 Color filter and solid state imaging device having a colored pattern formed from a curable composition FUJIFILM CORPORATION (JP) 2012-08-28 US disclosed
US-6214623-B1 Time-temperature indicator devices EASTMAN KODAK COMPANY 2001-04-10 US disclosed
WO-2000056274-A1 BODY COATING COMPOSITION PYRAMID PRODUCTIONS, INC. (US) 2000-09-28 WO disclosed
EP-0930488-A2 Time temperature indicator devices EASTMAN KODAK COMPANY (US) 1999-07-21 EP disclosed
US-5896297-A Robotube delivery system VALERINO SR FRED M (US) 1999-04-20 US disclosed
EP-0610994-B1 Photographic elements for producing blue, green and red exposure records of the same hue and methods for the retrieval and differentiation of the exposure records KODAK LTD (GB) 1997-12-10 EP disclosed
US-5420003-A SIMPLIFIED FILM AND PROCESSING FOR COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1995-05-30 US disclosed
US-5350650-A Color separations, scanning developed image with colored light beams modulated by dye images, computer recording and processsing of data EASTMAN KODAK COMPANY (US) 1994-09-27 US disclosed
US-4707297-A Removable guidepath for automated guidance vehicles BELL & HOWELL COMPANY (US) 1987-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220017474-A1 Novel Polycyclic Compound CUTA, DSG1, UACA METAP1 4754/4885MAPT 295/4885LMNA 580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.