SCHEMBL6328621

SCHEMBL6328621

O=[N+]([O-])c1ccc(N[C@H](CO)Cc2ccccc2)nc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.59
POLB P06746 1/20 0.59
MAPT P10636 6/20 0.52
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
LMNA P02545 2/20 0.52
NPC1 O15118 4/20 0.49
ITGB1 P05556 1/20 0.47
ITGA4 P13612 1/20 0.47
GAA P10253 2/20 0.46
CYP1A2 P05177 1/20 0.46
JAK3 P52333 1/20 0.46
IRAK4 Q9NWZ3 1/20 0.46
ALDH1A1 P00352 5/20 0.46
HPGD P15428 1/20 0.46
RAB9A P51151 4/20 0.44
KDM4E B2RXH2 1/20 0.44
CCR6 P51684 1/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19630439 1.00 SMN1; SMN2 (0.59) SMN1; SMN2POLBMAPTMEN1KMT2A
SCHEMBL3933135 0.87 GAA (0.55) SMN1; SMN2POLBMAPTMEN1KMT2A
SCHEMBL6723042 0.80 GAA (0.51) SMN1; SMN2POLBMAPTMEN1KMT2A
SCHEMBL6421334 0.80 NPC1 (0.57) SMN1; SMN2POLBMAPTMEN1KMT2A
SCHEMBL2792543 0.76 GAA (0.56) SMN1; SMN2POLBMAPTMEN1KMT2A
SCHEMBL2792546 0.76 GAA (0.56) SMN1; SMN2POLBMAPTMEN1KMT2A
SCHEMBL5123863 0.76 MAPT (0.45) SMN1; SMN2MAPTMEN1KMT2ALMNA
SCHEMBL5123860 0.76 MAPT (0.45) SMN1; SMN2MAPTMEN1KMT2ALMNA
SCHEMBL5649144 0.74 SMN1; SMN2 (1.00) SMN1; SMN2POLBMAPTMEN1KMT2A
SCHEMBL23802828 0.74 LMNA (0.58) SMN1; SMN2POLBMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6941051-B2 Method for producing non-linear optical organic crystal film REVEO, INC. (US) 2005-09-06 US claimed
US-20040033038-A1 Method for producing non-linear optical organic crystal film XU JIANJUN (US) 2004-02-19 US claimed
US-6577798-B2 Method for producing non-linear optical organic crystal film REVEO, INC. 2003-06-10 US claimed
US-20020041427-A1 Method for producing non-linear optical organic crystal film REVEO, INC. 2002-04-11 US claimed
WO-2002008828-A2 COMPOSITE NONLINEAR OPTICAL FILM, METHOD OF PRODUCING THE SAME AND APPLICATIONS OF THE SAME REVEO, INC. (US) 2002-01-31 WO claimed
WO-2002006890-A2 METHOD FOR PRODUCING NON-LINEAR OPTICAL ORGANIC CRYSTAL FILM REVEO, INC. (US) 2002-01-24 WO claimed
US-6303056-B1 Composite nonlinear optical film, method of producing the same and applications of the same REVEO, INC. 2001-10-16 US claimed
EP-0473140-B1 Method of forming thin film on fiber end surface SUMITOMO ELECTRIC INDUSTRIES (JP) 1995-11-15 EP claimed
US-9831417-B2 Poling treatment method, magnetic field poling device, and piezoelectric film YOUTEC CO., LTD. (JP) 2017-11-28 US disclosed
US-20140191618-A1 POLING TREATMENT METHOD, PLASMA POLING DEVICE, PIEZOELECTRIC BODY AND MANUFACTURING METHOD THEREOF, FILM FORMING DEVICE AND ETCHING DEVICE, AND LAMP ANNEALING DEVICE YOUTEC CO., LTD. (JP) 2014-07-10 US disclosed
US-20130153813-A1 POLING TREATMENT METHOD, PLASMA POLING DEVICE, PIEZOELECTRIC SUBSTANCE, AND MANFACTURING METHOD THEREFOR YOUTEC CO. LTD. (JP) 2013-06-20 US disclosed
US-6941051-B2 Method for producing non-linear optical organic crystal film REVEO, INC. (US) 2005-09-06 US disclosed
US-20040033038-A1 Method for producing non-linear optical organic crystal film XU JIANJUN (US) 2004-02-19 US disclosed
US-6577798-B2 Method for producing non-linear optical organic crystal film REVEO, INC. 2003-06-10 US disclosed
US-6303056-B1 Composite nonlinear optical film, method of producing the same and applications of the same REVEO, INC. 2001-10-16 US disclosed
CN-1024373-C Infrared band laser detection board for organic frequency doubling material CHINESE ACAD INST CHEMISTRY (CN) 1994-04-27 CN disclosed
EP-0344735-B1 NON-LINEAR OPTICAL MATERIAL MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-08-04 EP disclosed
CN-1064937-A INFRARED BAND LASER DETECTING BOARD FOR ORGANIC DOUBLE-FREQUENCY MATERIAL CHEMICAL INST CHINESE ACADEMY (CN) 1992-09-30 CN disclosed
US-4985179-A VINYLIDENE CYANIDE COPOLYMER, ORGANIC CRYSTAL MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-01-15 US disclosed
EP-0344735-A2 Non-linear optical material MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-12-06 EP disclosed