Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335428 | 0.74 | P2RX7 (0.39) | P2RX7 | |
| SCHEMBL6326202 | 0.74 | CYP2C9 (0.43) | MAPK14 | |
| SCHEMBL6328756 | 0.73 | P2RX7 (0.36) | NOTUMP2RX7 | |
| SCHEMBL6330895 | 0.72 | CTSS (0.42) | — | |
| SCHEMBL6335435 | 0.72 | P2RX7 (0.35) | NOTUMP2RX7 | |
| SCHEMBL6336615 | 0.72 | MEN1 (0.40) | NOTUMP2RX7MAPK14 | |
| SCHEMBL6330655 | 0.71 | KMT2A (0.36) | NOTUMP2RX7MAPK14 | |
| SCHEMBL6327832 | 0.71 | HCRTR2 (0.40) | MAPK14 | |
| SCHEMBL6333186 | 0.70 | NOTUM (0.37) | NOTUMAADATCNR2 | |
| SCHEMBL6333390 | 0.70 | MEN1 (0.44) | P2RX7MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050085509-A1 | Piperidin-2-one derivative compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO. LTD. (JP) | 2005-04-21 | — | — | US | disclosed |
| EP-1447401-A1 | PIPERIDIN-2-ONE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085509-A1 | Piperidin-2-one derivative compounds and drugs containing these compounds as the active ingredient | MAPKAP1, MAPK1, MAPK8 | NOTUM 4022/4885P2RX7 2638/4885AADAT 4435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.