Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.55 |
| ▸ | CKS1B | P61024 | 1/20 | 0.55 |
| ▸ | SKP1 | P63208 | 1/20 | 0.55 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5785993 | 0.99 | KDM4E (0.71) | KDM4EALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL5786728 | 0.92 | ALDH1A1 (0.65) | KDM4EALDH1A1L3MBTL1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL6337335 | 0.90 | ALDH1A1 (0.63) | KDM4EALDH1A1L3MBTL1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL5789123 | 0.90 | ALDH1A1 (0.63) | KDM4EALDH1A1L3MBTL1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL6330957 | 0.90 | ALDH1A1 (0.63) | KDM4EALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL6331041 | 0.84 | ALDH1A1 (1.00) | KDM4EALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL6335702 | 0.83 | HPGD (1.00) | KDM4EALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL13793593 | 0.82 | HRH4 (0.54) | KDM4EALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL5787748 | 0.81 | ALDH1A1 (0.75) | KDM4EALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL4818110 | 0.81 | ALDH1A1 (1.00) | KDM4EALDH1A1L3MBTL1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096327-A1 | Novel norepinephrine reuptake inhibitors for the treatment of central nervous system disorders | WARNER-LAMBERT COMPANY LLC | 2005-05-05 | — | — | US | claimed |
| US-20050096327-A1 | Novel norepinephrine reuptake inhibitors for the treatment of central nervous system disorders | WARNER-LAMBERT COMPANY LLC | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096327-A1 | Novel norepinephrine reuptake inhibitors for the treatment of central nervous system disorders | SLC6A2, SLC18A2, SLC6A3 | KDM4E 1392/4885ALDH1A1 730/4885L3MBTL1 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.