Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248039 | 0.85 | ALDH1A1 (0.47) | LMNAMAPT | |
| SCHEMBL6249983 | 0.85 | ALDH1A1 (0.47) | LMNAMAPT | |
| SCHEMBL25259239 | 0.76 | HRH1 (0.47) | LMNATSHR | |
| SCHEMBL25216672 | 0.76 | HRH1 (0.47) | LMNATSHR | |
| SCHEMBL25218614 | 0.76 | HRH1 (0.47) | LMNATSHR | |
| SCHEMBL6646996 | 0.76 | CYP1A2 (0.52) | KEAP1LMNAMAPTTSHR | |
| SCHEMBL6247356 | 0.74 | ALDH1A1 (0.46) | LMNAMAPT | |
| SCHEMBL6329021 | 0.72 | SMN1; SMN2 (0.38) | ABCB1LMNA | |
| SCHEMBL4853522 | 0.69 | LMNA (0.49) | LMNA | |
| SCHEMBL6644528 | 0.69 | TSHR (0.55) | KEAP1HCRTR1HCRTR2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916822-B2 | Phenoxyalkylamine derivatives useful as opioid δ receptor agonists | MEIJI SEIKA KAISHA, LTD. (JP) | 2005-07-12 | — | — | US | disclosed |