Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | DCK | P27707 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL928241 | 0.81 | CHRNA7 (0.60) | KDM1ACHRNB2CHRNA7CHRNA4CYP11B1 | |
| SCHEMBL6329284 | 0.81 | KDM1A (0.38) | USP30KDM1AACKR3MMP13GPR119 | |
| SCHEMBL6324400 | 0.79 | CHRNB2 (0.53) | PDE10AUSP30CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL652572 | 0.77 | PDE10A (0.54) | PDE10AUSP30GPR119OPRM1OPRD1 | |
| SCHEMBL652571 | 0.77 | PDE10A (0.54) | PDE10AUSP30GPR119OPRM1OPRD1 | |
| SCHEMBL930345 | 0.77 | CHRNB2 (0.60) | KDM1ACHRNB2CHRNA7CHRNA4CYP11B1 | |
| Trifluoroacetic Acid SCHEMBL1789639 | 0.77 | CHRNB2 (0.53) | KDM1ACHRNB2CHRNA7CHRNA4CYP11B1 | |
| SCHEMBL31173949 | 0.77 | GPR119 (0.46) | PDE10AUSP30GPR119 | |
| SCHEMBL10256688 | 0.77 | GPR119 (0.46) | PDE10AUSP30GPR119 | |
| SCHEMBL6323845 | 0.76 | CHRNB2 (0.47) | PDE10AUSP30CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065178-A1 | Substituted diazabicycloakane derivatives | ABBOTT LABORATORIES | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065178-A1 | Substituted diazabicycloakane derivatives | CHRNA7, CHRNA1, CHRNA5 | PDE10A 1088/4885USP30 4503/4885KDM1A 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.