Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12780432 | 0.86 | MEN1 (0.59) | TAS1R3TAS1R1PDE4DKMT2AALDH1A1 | |
| SCHEMBL6136939 | 0.86 | TAS1R3 (0.53) | TAS1R3TAS1R1PDE4DKMT2AALDH1A1 | |
| SCHEMBL2166529 | 0.85 | GSK3B (0.54) | TAS1R3TAS1R1PDE4DKMT2AALDH1A1 | |
| SCHEMBL9155650 | 0.85 | PDE4D (0.54) | TAS1R3TAS1R1PDE4DKMT2AALDH1A1 | |
| SCHEMBL29620782 | 0.85 | GSK3B (0.54) | TAS1R3TAS1R1PDE4DKMT2AALDH1A1 | |
| SCHEMBL22570710 | 0.85 | TAS1R3 (0.51) | TAS1R3TAS1R1PDE4DKMT2AALDH1A1 | |
| SCHEMBL3893527 | 0.84 | TSHR (0.66) | PDE4DKMT2AALDH1A1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL29393777 | 0.83 | TAS1R3 (0.50) | TAS1R3TAS1R1PDE4DKMT2AALDH1A1 | |
| SCHEMBL3950960 | 0.83 | TAS1R3 (0.57) | TAS1R3TAS1R1PDE4DALDH1A1MAPT | |
| SCHEMBL23782335 | 0.82 | TAS1R3 (0.56) | TAS1R3TAS1R1PDE4DMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABOTT LABORATORIES | 2005-09-22 | — | — | US | disclosed |
| US-20050187387-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBOTT LABORATORIES | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | TAS1R3 90/4885TAS1R1 74/4885PDE4D 1827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.