Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321623 | 0.86 | MC4R (1.00) | MC4R | |
| SCHEMBL6322785 | 0.86 | MC4R (1.00) | MC4R | |
| Hydrochloric Acid SCHEMBL6322971 | 0.85 | MC4R (0.98) | MC4R | |
| Hydrochloric Acid SCHEMBL6321736 | 0.85 | MC4R (0.98) | MC4R | |
| SCHEMBL6321344 | 0.84 | MC4R (1.00) | MC4R | |
| SCHEMBL6321892 | 0.79 | MC4R (1.00) | MC4R | |
| SCHEMBL6324577 | 0.75 | MC4R (0.77) | MC4R | |
| Hydrochloric Acid SCHEMBL6321995 | 0.75 | MC4R (0.98) | MC4R | |
| SCHEMBL6323922 | 0.74 | MC4R (0.80) | MC4R | |
| SCHEMBL6329105 | 0.74 | MC4R (0.72) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949552-B2 | Remedial agent for anxiety neurosis or depression and piperazine derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20030186992-A1 | Remedial agent for anxiety neurosis or depression and piperazine derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1295608-A1 | REMEDIAL AGENT FOR ANXIETY NEUROSIS OR DEPRESSION AND PIPERAZINE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2003-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186992-A1 | Remedial agent for anxiety neurosis or depression and piperazine derivative | CNR1, HTR4, TPH1 | MC4R 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.