Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.56 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.44 |
| ▸ | TK2 | O00142 | 2/20 | 0.43 |
| ▸ | TK1 | P04183 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25395896 | 1.00 | TOP2A (0.56) | TOP2ARNASE1HDAC1TK2TK1 | |
| SCHEMBL25401183 | 1.00 | TOP2A (0.56) | TOP2ARNASE1HDAC1TK2TK1 | |
| SCHEMBL6329589 | 1.00 | TOP2A (0.56) | TOP2ARNASE1HDAC1TK2TK1 | |
| SCHEMBL6323173 | 0.90 | RNASE1 (0.51) | TOP2ARNASE1TK2TK1 | |
| SCHEMBL5693267 | 0.88 | TOP2A (0.49) | TOP2ARNASE1TK2TK1 | |
| SCHEMBL4731659 | 0.88 | TOP2A (0.49) | TOP2ARNASE1TK2TK1 | |
| SCHEMBL6830424 | 0.87 | RNASE1 (0.49) | TOP2ARNASE1TK2TK1 | |
| SCHEMBL25399262 | 0.87 | DUT (0.46) | TOP2ARNASE1 | |
| SCHEMBL25400848 | 0.87 | RNASE1 (0.63) | RNASE1TK2TK1 | |
| SCHEMBL4808054 | 0.87 | RNASE1 (0.63) | RNASE1TK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875860-B2 | Method for purifying 5′ -protected thymidines and novel derivatives thereof | MITSUI CHEMICALS, INC. (JP) | 2005-04-05 | — | — | US | disclosed |
| EP-1258489-B1 | Method for purifying 5'-protected thymidines | MITSUI CHEMICALS INC (JP) | 2004-09-08 | — | — | EP | disclosed |
| US-20030004331-A1 | Method for purifying 5' -protected thymidines and novel derivatives thereof | MITSUI CHEMICALS, INC. (JP) | 2003-01-02 | — | — | US | disclosed |
| EP-1258489-A1 | Method for purifying 5'-protected thymidines | Mitsui Chemicals, Inc. (JP) | 2002-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004331-A1 | Method for purifying 5' -protected thymidines and novel derivatives thereof | TYMP, TYMS, DUT | TOP2A 43/4885RNASE1 601/4885HDAC1 1460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.