Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | IL6ST | P40189 | 1/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DNM2 | P50570 | 4/20 | 0.45 |
| ▸ | HTR6 | P50406 | 4/20 | 0.45 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967590 | 0.83 | CDC25A (0.66) | CDC25AICMTDNM2 | |
| SCHEMBL9701531 | 0.81 | CDC25A (0.49) | CDC25AOXER1ICMTPOLBDNM2 | |
| SCHEMBL8758280 | 0.80 | HTR2A (0.57) | HTR6ALOX5MEN1KMT2A | |
| SCHEMBL15700113 | 0.80 | POLB (0.52) | IL6STICMTPOLBHTR6PADI4 | |
| SCHEMBL1520654 | 0.78 | ALOX5 (0.52) | ICMTPOLBHTR6ALOX5MEN1 | |
| SCHEMBL6111306 | 0.78 | ALOX5 (0.49) | ICMTPOLBHTR6ALOX5MEN1 | |
| SCHEMBL8335058 | 0.78 | ALOX5 (0.49) | ICMTPOLBHTR6ALOX5MEN1 | |
| SCHEMBL24199373 | 0.76 | KMT2A (0.51) | ICMTPOLBALOX5MEN1KMT2A | |
| SCHEMBL5553536 | 0.75 | PDE4B (0.38) | MEN1KMT2A | |
| SCHEMBL8126918 | 0.75 | CDC25A (0.64) | CDC25AIL6STICMTPOLBDNM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419430-A2 | NOVEL COMPOUNDS OF REVERSE-TURN MIMETICS, METHOD FOR MANUFACTURING THE SAME AND USE THEREOF | JW Pharmaceutical Corporation (KR) | 2012-02-22 | — | — | EP | claimed |
| US-20100267672-A1 | NOVEL COMPOUNDS OF REVERSE-TURN MIMETICS, METHOD FOR MANUFACTURING THE SAME AND USE THEREOF | CHOONGWAE PHARMA CORPORATION (KR) | 2010-10-21 | — | — | US | claimed |
| WO-2010120112-A2 | NOVEL COMPOUNDS OF REVERSE-TURN MIMETICS, METHOD FOR MANUFACTURING THE SAME AND USE THEREOF | CHOONGWAE PHARMA CORPORATION (KR) | 2010-10-21 | — | — | WO | claimed |
| EP-2419430-A2 | NOVEL COMPOUNDS OF REVERSE-TURN MIMETICS, METHOD FOR MANUFACTURING THE SAME AND USE THEREOF | JW Pharmaceutical Corporation (KR) | 2012-02-22 | — | — | EP | disclosed |
| US-20100267672-A1 | NOVEL COMPOUNDS OF REVERSE-TURN MIMETICS, METHOD FOR MANUFACTURING THE SAME AND USE THEREOF | CHOONGWAE PHARMA CORPORATION (KR) | 2010-10-21 | — | — | US | disclosed |
| WO-2010120112-A2 | NOVEL COMPOUNDS OF REVERSE-TURN MIMETICS, METHOD FOR MANUFACTURING THE SAME AND USE THEREOF | CHOONGWAE PHARMA CORPORATION (KR) | 2010-10-21 | — | — | WO | disclosed |
| EP-0022634-B1 | ACYLATED INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND DRUGS COMPRISING THEM | TEIJIN LIMITED (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0022634-A1 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them | TEIJIN LIMITED (JP) | 1981-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267672-A1 | NOVEL COMPOUNDS OF REVERSE-TURN MIMETICS, METHOD FOR MANUFACTURING THE SAME AND USE THEREOF | MCL1, THPO, FLT3 | CDC25A 1447/4885IL6ST 1379/4885OXER1 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.