Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | ICMT | O60725 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | DNM2 | P50570 | 4/20 | 0.46 |
| ▸ | HTR6 | P50406 | 5/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.45 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632967 | 0.81 | CDC25A (0.48) | CDC25AICMTPOLBDNM2HTR6 | |
| SCHEMBL27501032 | 0.80 | OXER1 (0.46) | CDC25AICMTCNR2POLBHTR6 | |
| SCHEMBL27561384 | 0.79 | POLB (0.74) | POLBHTR6PADI4 | |
| SCHEMBL11623320 | 0.79 | POLB (0.57) | CDC25AICMTCNR2POLBDNM2 | |
| SCHEMBL10967590 | 0.78 | CDC25A (0.66) | CDC25AICMTCNR2DNM2 | |
| SCHEMBL10146987 | 0.76 | HTR2A (0.67) | — | |
| SCHEMBL9701331 | 0.75 | HTR6 (0.62) | POLBHTR6 | |
| SCHEMBL3449953 | 0.75 | POLB (0.63) | CDC25AICMTCNR2POLBDNM2 | |
| SCHEMBL23269921 | 0.74 | CDC25A (0.65) | CDC25AICMTCNR2DNM2 | |
| SCHEMBL17943470 | 0.74 | CDC25A (0.57) | CDC25AICMTCNR2POLBDNM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132319-A | Antiasthmatic, antiinflammatory, antiallergen and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-07-21 | — | — | US | disclosed |